Dreyfuss P, Michaelsen M, Fletcher D
Neuro-Skeletal Center, Tyler, Texas.
Spine (Phila Pa 1976). 1994 May 15;19(10):1125-31. doi: 10.1097/00007632-199405001-00005.
Five asymptomatic subjects underwent provocative injections of the lateral atlanto-axial and atlanto-occipital joints.
This study isolated and stimulated the lateral atlanto-axial and atlanto-occipital joints via fluoroscopically guided intra-articular injections to determine if they are potential pain generators. If they are pain generators, preliminary pain pattern maps will be constructed.
The cervical zygapophyseal joints (C2-3 to C6-7) are potential pain generators as demonstrated by referred pain induced via isolated intra-articular joint injections in normal subjects. Tentative referral patterns based on direct mechanical stimulation of the lateral atlanto-axial and atlanto-occipital joints have not been reported.
Five volunteers without histories of upper cervical pain underwent two joint injections each. In all five subjects, the left atlanto-occipital and right lateral atlanto-axial joints were stimulated via injection of contrast medium causing distension of the joint capsule.
Referred pain was produced with all ten injections. The lateral atlanto-axial injections resulted in consistent referral patterns, whereas the atlanto-occipital referral patterns varied significantly. A tentative composite diagram of the experimentally induced pain was created for each joint.
This study confirms the nociceptive ability of these cervical synovial joints. This study may assist the clinician in the differential diagnosis of head and neck pain.
五名无症状受试者接受了寰枢外侧关节和寰枕关节的激发性注射。
本研究通过在荧光镜引导下进行关节内注射来分离并刺激寰枢外侧关节和寰枕关节,以确定它们是否为潜在的疼痛源。如果它们是疼痛源,将构建初步的疼痛模式图。
如正常受试者通过单独的关节内注射诱发牵涉痛所证明的,颈椎关节突关节(C2-3至C6-7)是潜在的疼痛源。基于对寰枢外侧关节和寰枕关节的直接机械刺激的初步牵涉模式尚未见报道。
五名无上颈椎疼痛病史的志愿者每人接受两次关节注射。在所有五名受试者中,通过注射造影剂使关节囊扩张来刺激左侧寰枕关节和右侧寰枢外侧关节。
所有十次注射均产生了牵涉痛。寰枢外侧关节注射产生了一致的牵涉模式,而寰枕关节的牵涉模式则有显著差异。为每个关节绘制了实验诱发疼痛的初步综合图。
本研究证实了这些颈椎滑膜关节的伤害感受能力。本研究可能有助于临床医生对头颈部疼痛进行鉴别诊断。