胚胎发育不良性神经上皮肿瘤中的黑色素分化

Melanotic differentiation in dysembryoplastic neuroepithelial tumor.

作者信息

Elizabeth J, Bhaskara R M, Radhakrishnan V V, Radhakrishnan K, Thomas S V

机构信息

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.

出版信息

Clin Neuropathol. 2000 Jan-Feb;19(1):38-40.

PMID:10774951

Abstract

Dysembryoplastic neuroepithelial tumor (DNT) is an uncommon intracranial tumor which is usually encountered in patients with medically intractable complex partial seizures of temporal lobe origin. Melanotic differentiation in a DNT has not been reported previously. Herewith we report a case of DNT with unique melanotic differentiation in a 23-year-old female who presented with medically intractable epilepsy. She underwent craniotomy and tumor decompression with a good outcome. We present the histopathological features of DNT with melanotic differentiation and discuss its prognostic significance.

摘要

胚胎发育不良性神经上皮肿瘤（DNT）是一种罕见的颅内肿瘤，常见于患有药物难治性颞叶起源复杂部分性癫痫的患者。此前尚未有DNT发生黑色素分化的报道。在此，我们报告一例23岁患有药物难治性癫痫的女性患者，其DNT具有独特的黑色素分化。她接受了开颅手术和肿瘤减压，预后良好。我们展示了具有黑色素分化的DNT的组织病理学特征，并讨论了其预后意义。