Mathur M L, Dixit A K
Desert Medicine Research Centre, (Indian Council of Medical Research), Jodhpur.
Indian J Physiol Pharmacol. 1999 Jul;43(3):347-54.
The study assesses the relationship of selected demographic, anthropometric, radiological, work-history and smoking-history related variables with Forced Vital Capacity (FVC) in a sample of 168 sand stone quarry workers in a desert environment. Except the variables related to smoking behaviour, all are found significantly associated with FVC. The predictors of FVC screened through the multiple regression analysis were age, weight, height, profusion of opacities in chest X-ray and duration of work. Mean FVC was found significantly lower as compared to the healthy adult population. On an average FVC% was 90% of predicted (Percentage deviation of 10%). A clear increasing trend in FVC% along age/duration of work was observed among the young workers, which may be due to building of muscles in this job. Percentage deviation of 20% or more in FVC was significantly associated with presence of radiological opacities suggestive of silicosis (odds Ratio = 3.3). The diagnostic utility of the same is also assessed.
该研究评估了在沙漠环境中选取的168名砂岩采石场工人样本中,特定的人口统计学、人体测量学、放射学、工作史和吸烟史相关变量与用力肺活量(FVC)之间的关系。除了与吸烟行为相关的变量外,其他所有变量均被发现与FVC显著相关。通过多元回归分析筛选出的FVC预测因素为年龄、体重、身高、胸部X光片上的阴影密集度和工作时长。与健康成年人群相比,FVC均值显著更低。平均FVC%为预测值的90%(偏差百分比为10%)。在年轻工人中观察到FVC%随年龄/工作时长呈明显上升趋势,这可能是由于该工作中肌肉的锻炼。FVC偏差20%或更多与提示矽肺的放射学阴影显著相关(比值比 = 3.3)。同时还评估了其诊断效用。