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作为铁强化剂的Fe(III)-EDTA络合物。进一步研究。

Fe(III)-EDTA complex as iron fortification. Further studies.

作者信息

Martínez-Torres C, Romano E L, Renzi M, Layrisse M

出版信息

Am J Clin Nutr. 1979 Apr;32(4):809-16. doi: 10.1093/ajcn/32.4.809.

Abstract

The data presented confirm the advantages of Fe(III)-EDTA as a salt for iron fortification. This iron compound exchanges completely with intrinsic wheat iron in the lumen of the gut. The iron absorption data from this salt tested with six different food vehicles compared with the absorption of ferrous sulfate administered with the same vehicles indicate that while the mean absorption from ferrous sulfate varies from 2 to 30% according to the food vehicle mixed with the salt, the absorption from Fe(III)-EDTA remains practically the same. Apparently, the iron absorption from Fe(III)-EDTA complex is slightly or not affected by the presence of vegetable foods or milk. All these data suggest that only a small amount of iron from this salt, about 10 mg/day, would be necessary to prevent iron deficiency anemia even in those populations relying for their subsistence on vegetable food only.

摘要

所呈现的数据证实了Fe(III)-EDTA作为铁强化盐的优势。这种铁化合物在肠道腔内与小麦固有铁完全交换。用六种不同食物载体测试该盐的铁吸收数据,并与用相同载体施用的硫酸亚铁的吸收情况进行比较,结果表明,虽然硫酸亚铁的平均吸收率根据与盐混合的食物载体不同而在2%至30%之间变化,但Fe(III)-EDTA的吸收率几乎保持不变。显然,Fe(III)-EDTA络合物的铁吸收受植物性食物或牛奶的存在影响很小或不受影响。所有这些数据表明,即使在那些仅以植物性食物为生的人群中,每天只需摄入少量这种盐中的铁(约10毫克)就足以预防缺铁性贫血。

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