Patial R K
IG Medical College, Shimla, HP.
J Assoc Physicians India. 1999 May;47(5):503-4.
To evaluate the radiological miliary shadows in the high landers of a Himalayan desert for the presence of silicosis.
Seventeen high landers attending the Medicine OPD of a multi-speciality medical camp at Kaza in Himalayas (height 12,500 feet above sea level) having radiological miliary shadows were included in the study. A detailed life time work place history was taken. In the laboratory workup their hemogram, repeat chest skiagram, peak expiratory flow rate, urinalysis and electrocardiogram were undertaken. Their localities were looked for the presence of industries particularly for silicosis prone work place. The silica contents of upper strata of soil were estimated.
Silicosis--chronic simple variety was present in nine males and eight females. The youngest person was 43 years of age and oldest person was of 65 years of age. There was no silicosis prone industry in their locality. Four had taken repeated courses of anti-tubercular treatment in adequate doses for these miliary shadows without any change in the radiological shadows. Three had silicosis prone work history. Seven were smokers and two had hypertension. The miliary shadows were 2-4 mm in size and hilar lymphadenopathy was in 11 and fine calcification of lymph nodes in two. Peak expiratory flow rate was reduced. Upper strata of soil had a silica content of 36.8 percent.
Silicosis developed in high landers of the Himalayas even without working in silicosis prone work place. They were exposed to silica from the non-work place silica rich environment.
评估喜马拉雅沙漠高地居民的放射学粟粒样阴影，以确定是否存在矽肺。
本研究纳入了17名在喜马拉雅山脉卡扎（海拔12,500英尺）的多专科医疗营地内科门诊就诊、有放射学粟粒样阴影的高地居民。详细询问了他们一生的工作场所史。在实验室检查中，进行了血常规、重复胸部X光检查、呼气峰值流速、尿液分析和心电图检查。查看他们所在地区是否存在工业，特别是矽肺易感工作场所。估算了土壤上层的二氧化硅含量。
9名男性和8名女性患有慢性单纯性矽肺。最年轻的患者43岁，最年长的65岁。他们所在地区没有矽肺易感行业。4人因这些粟粒样阴影接受了足够剂量的反复抗结核治疗，但放射学阴影没有任何变化。3人有矽肺易感工作史。7人吸烟，2人患有高血压。粟粒样阴影大小为2 - 4毫米，11人有肺门淋巴结肿大，2人有淋巴结细小钙化。呼气峰值流速降低。土壤上层二氧化硅含量为36.8%。
喜马拉雅山脉的高地居民即使没有在矽肺易感工作场所工作也会患上矽肺。他们是在非工作场所富含二氧化硅的环境中接触到二氧化硅的。
