Dean S W
Covance Laboratories Ltd, Harrogate, North Yorkshire, UK.
Lab Anim. 1999 Oct;33(4):309-27. doi: 10.1258/002367799780487823.
There is a wealth of information in the published literature which describes a multitude of approaches to enriching the environment of laboratory animals. This paper attempts to review the various methods of enrichment through social contact, enhancement of the environment and diet, and improvements in husbandry. It attempts to place the various enrichment initiatives within the context of a laboratory which conducts regulatory toxicology, describes some of the experiences in the author's own laboratory and attempts to highlight those ideas which might prove practical to implement in the future. The aim is to demonstrate that a creative approach to environmental enrichment is indeed compatible with regulatory toxicology. It is hoped that this will encourage those responsible for the care and welfare of animals in such a laboratory to challenge historical practices and include environmental enrichment as a fundamental necessity of study design.
已发表的文献中有大量信息描述了多种丰富实验动物环境的方法。本文试图综述通过社交接触、改善环境和饮食以及改进饲养管理等方式进行环境富集的各种方法。本文试图将各种富集措施置于一个进行法规毒理学研究的实验室背景下，描述作者所在实验室的一些经验，并试图突出那些未来可能证明切实可行的想法。目的是证明创造性的环境富集方法确实与法规毒理学相兼容。希望这将鼓励此类实验室中负责动物照料和福利的人员挑战传统做法，并将环境富集作为研究设计的基本必要条件纳入其中。
