Mantis P, Lamb C R
Department of Small Animal Medicine and Surgery, Royal Veterinary College, University of London, North Mymms, Hertfordshire, UK.
Vet Radiol Ultrasound. 2000 Mar-Apr;41(2):164-6. doi: 10.1111/j.1740-8261.2000.tb01471.x.
The medullary rim sign is a distinct hyperechoic line in the renal medulla parallel to the corticomedullary junction that has been reported in dogs with a variety of renal diseases. To examine the association between medullary rim sign and renal disease, the medical records of thirty-two dogs that had medullary rim sign were reviewed retrospectively. Eighteen dogs (56%) had no evidence of renal dysfunction; 14 (44%) had clinicopathological evidence of renal disease, including 6 (19%) that had hypercalcemic nephropathy. Most dogs (72%) in which medullary rim sign was the only ultrasonographic finding affecting the kidneys had no evidence of renal dysfunction. In contrast, 78% dogs that had medullary rim sign and other renal signs (reduced size, increased medullary echogenicity, and pyelectasia) had renal disease. On the basis of this study, the medullary rim sign appears to be a non-specific ultrasonographic sign; however, the possibility cannot be excluded that is a sentinel sign of subclinical renal disease.
肾髓质边缘征是指在患有多种肾脏疾病的犬类中，于肾髓质内出现的一条与肾皮质髓质交界平行的明显高回声线。为研究肾髓质边缘征与肾脏疾病之间的关联，我们回顾性分析了32例出现肾髓质边缘征的犬类的病历。18只犬（56%）无肾功能不全的证据；14只（44%）有肾脏疾病的临床病理证据，其中6只（19%）患有高钙血症肾病。大多数（72%）肾髓质边缘征是唯一影响肾脏的超声检查结果的犬类无肾功能不全的证据。相比之下，78%出现肾髓质边缘征及其他肾脏体征（肾脏体积减小、肾髓质回声增强和肾盂积水）的犬患有肾脏疾病。基于本研究，肾髓质边缘征似乎是一种非特异性超声征象；然而，不能排除其为亚临床肾脏疾病前哨征象的可能性。
