“阳性”和“阴性”精神分裂症中的定量脑电图
Quantitative EEG in 'positive' and 'negative' schizophrenia.
作者信息
Begić D, Hotujac L, Jokić-Begić N
机构信息
University Department of Psychiatry, Clinical Hospital Center Rebro, Zagreb, Croatia.
出版信息
Acta Psychiatr Scand. 2000 Apr;101(4):307-11.
OBJECTIVE
Quantitative EEG has yielded different results in schizophrenia. The method of quantitative EEG has been relatively poorly used in the studies of the dichotomy into positive and negative schizophrenia.
METHOD
Amplitude values of any particular frequency band (after fast Fourier transformation, FFT) were observed in 47 schizophrenic patients (25 patients with positive and 22 patients with negative schizophrenia) and in 50 normal subjects. The frontal, temporal, parietal and occipital regions (F3, F4, C3, C4, T3, T4, P3, P4, O1 and O2) were observed.
RESULTS
Positive and negative schizophrenia were found to differ only in the delta and theta bands over frontal regions. Positive and negative schizophrenic patients were found to differ from normal subjects in delta, theta, alpha and beta 2 bands.
CONCLUSION
Delta and theta activity may play a role as a marker in differentiating between positive and negative schizophrenia.
目的
定量脑电图在精神分裂症研究中得出了不同结果。在将精神分裂症分为阳性和阴性的研究中，定量脑电图方法的应用相对较少。
方法
观察了47例精神分裂症患者（25例阳性精神分裂症患者和22例阴性精神分裂症患者）以及50名正常受试者在任何特定频段（经快速傅里叶变换，FFT后）的振幅值。观察了额叶、颞叶、顶叶和枕叶区域（F3、F4、C3、C4、T3、T4、P3、P4、O1和O2）。
结果
发现阳性和阴性精神分裂症仅在额叶区域的δ波和θ波频段存在差异。发现阳性和阴性精神分裂症患者在δ波、θ波、α波和β2波频段与正常受试者存在差异。
结论
δ波和θ波活动可能作为区分阳性和阴性精神分裂症的一个标志物发挥作用。
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