Hadi U, Tohmeh H, Maalouf R
Department of Otolaryngology Head and Neck Surgery, American University of Beirut Medical Center Lebanon, New York, NY 10022-6297, USA.
Eur Arch Otorhinolaryngol. 2000;257(2):77-9. doi: 10.1007/pl00007514.
Squamous cell carcinoma (SCC) of the skin usually occurs in older patients and commonly develops from actinic keratosis. Patients with xeroderma pigmentosum (XP) can acquire SCC at an early age. To our knowledge the youngest reported patient with XP and SCC was 8 years of age. We report a 19-month-old Lebanese girl with XP who presented clinically because of a rapidly growing mass of the medial part of her right lower lid that was biopsied and found to be squamous cell carcinoma. The mass was surgically excised with no evidence of recurrence after 2 years of follow-up. We describe our clinical experiences with this patient and have reviewed the available literature concerning XP and malignancy.
皮肤鳞状细胞癌（SCC）通常发生于老年患者，且常由光化性角化病发展而来。着色性干皮病（XP）患者在早年即可罹患SCC。据我们所知，报道的最年轻的XP合并SCC患者为8岁。我们报告一例19个月大的黎巴嫩女童，患有XP，因右眼下睑内侧迅速增大的肿物前来就诊，活检发现为鳞状细胞癌。该肿物经手术切除，随访2年无复发迹象。我们描述了对此患者的临床经验，并复习了有关XP与恶性肿瘤的现有文献。
