Vineberg A
Isr J Med Sci. 1975 Feb-Mar;11(2-3):250-63.
Myocardial mammary artery implants revascularize via the undiseased coronary microcirculation. Such implants, followed for up to 20 years, showed no atherosclerosis, while the coronary arteries of the patients became totally occluded. Implant patency with collateralization was 80%; some patients were living entirely on blood supplied by mammary implants. Operative mortality was 2%. There was improvement in anginal pain in 85% of the cases and in left ventricular failure, in 67%. Studies of 43 patients with single implants, followed for up to 20 years, showed that 54% survived for an average of eight years and 46% have survived for an average of 12 years, and are still living. Double-ventricular implants in 42 patients with triple coronary artery disease showed that 90.5% survived for an average of five years, compared with 53% for medically treated patients. The technique of mammary implants is described and the procedure is compared to aortocoronary bypass grafts.
心肌乳内动脉植入物通过未患病的冠状动脉微循环实现血管重建。对这类植入物长达20年的随访显示,植入物未出现动脉粥样硬化,而患者的冠状动脉却完全闭塞。植入物通畅并伴有侧支循环形成的比例为80%;一些患者完全依靠乳内动脉植入物供应的血液维持生命。手术死亡率为2%。85%的病例心绞痛症状得到改善,67%的病例左心室衰竭情况有所改善。对43例接受单支植入物的患者进行长达20年的随访研究发现,54%的患者存活平均8年,46%的患者存活平均12年,目前仍在世。对42例三支冠状动脉疾病患者进行双心室植入物手术的结果显示,90.5%的患者存活平均5年,而接受药物治疗的患者这一比例为53%。本文描述了乳内动脉植入技术,并将该手术与主动脉冠状动脉搭桥术进行了比较。