Athanasoulis C A, Baum S, Rösch J, Waltman A C, Ring E J, Smith J C, Sugarbaker E, Wood W
Am J Surg. 1975 Feb;129(2):212-6. doi: 10.1016/0002-9610(75)90300-1.
Twenty-four patients with massive rectal hemorrhage and known or subsequently proved colonic diverticular disease had the bleeding site localized by mesenteric angiography and received intra-arterial infusion of vasopressin to arrest the bleeding. In twenty-two patients the bleeding was controlled with the vasopressin infusion whereas in the remaining two, hemorrhage did not stop and surgery was performed. Of the twenty-two patients in whom bleeding was arrested by vasopressin infusion, twelve received no further surgical therapy, five had elective prophylactic surgical resection after a period of hemostasis, and the remaining five underwent segmental resection for bleeding that recurred after cessation of the infusion. Of the twelve patients who were not operated on, three had rebleeding two, four, and twelve months after vasopressin infusion and two of these three patients required surgery. The remaining nine have had no recurrent bleeding for periods ranging from seven to thirty-four months. Of ten patients who had segmental resection after precise localization of the bleeding site and initial control with vasopressin, no one has had recurrent hemorrhage for periods ranging from two to eighteen months.
24例有大量直肠出血且已知或随后证实患有结肠憩室病的患者，通过肠系膜血管造影确定出血部位，并接受动脉内输注血管加压素以止血。22例患者通过输注血管加压素控制了出血，而其余2例出血未停止，接受了手术治疗。在通过输注血管加压素止血的22例患者中，12例未接受进一步的手术治疗，5例在止血一段时间后接受了择期预防性手术切除，其余5例因输注停止后出血复发而接受了节段性切除。在未接受手术的12例患者中，3例在输注血管加压素后2个月、4个月和12个月再次出血，这3例患者中有2例需要手术。其余9例在7至34个月期间未再次出血。在10例在出血部位精确定位并最初用血管加压素控制后接受节段性切除的患者中，没有人在2至18个月期间出现复发性出血。
