von Barsewisch B
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975;193(3):197-204. doi: 10.1007/BF00440978.
The phenomenon of unilateral leukodiapedesis is demonstrated in the irritated conjunctiva of rabbits and rhesus-monkeys. The leukocytes will penetrate the vessel walls first in the neighbourhood of the irritation. This can be demonstrated during the first minutes after the onset of an inflammatory reaction only, i.e. prior to a general leukocytosis of the tissue. By fixation with glutaraldehyde or osmium-tetroxyde the dynamic movement can be visualized and the directions of the irritation and of the migration are obvious in the conjunctiva. So this tissue provides an excellent model to demonstrate the unilateral sticking and the directed migration of leukocytes through vessel walls, a fact to which references seem to be missing in the ophthalmopathologic and pathologic literature.
在家兔和恒河猴受刺激的结膜中证实了单侧白细胞渗出现象。白细胞会首先在刺激部位附近穿透血管壁。这只能在炎症反应开始后的最初几分钟内得到证实,即在组织出现全身性白细胞增多之前。通过用戊二醛或四氧化锇固定,可以观察到动态运动,并且在结膜中刺激和迁移的方向很明显。因此,该组织提供了一个极好的模型来证明白细胞通过血管壁的单侧黏附和定向迁移,而这一事实在眼科病理学和病理学文献中似乎没有提及。