[Risk factors of ischemic heart disease and lipid metabolism in cardiorespiratory diseases].

Clinicobiochemical parameters and factors of risk of ischemic heart disease in patients with cardiorespiratory diseases (CRD) were examined for correlations. The risk factors, impairment of lipid spectrum and antioxidant defense were assessed in patients aged 27 to 70 years with CRD. The patients were divided into three groups: patients with chronic nonspecific pulmonary diseases (CNSPD), ischemic heart disease patients (IHD), those with CNSPD plus IHD. The results suggest that in CNSPD patients such risk factors as smoking, low physical activity, stress, arterial hypertension, hereditary predisposition to IHD occurred in more than 50% of cases. Compared to IHD patients, these patients' dyslipoproteinemia was characterized by greater frequency of hypercholesterolemia and less frequency of hypoalphacholesterolemia. Combination of atherosclerosis with CNSPD aggravates the course of vascular disorders.