Ferlan-Marolt V, Vladislav P, Alojz P
Institute of Pathology, University of Ljubljana, Slovenia.
Hepatogastroenterology. 2000 Mar-Apr;47(32):556-9.
A smooth muscle tumor originating from the pancreas is an extremely rare neoplasm characterized by peculiar histopathologic features and progressive clinical course. We report a case of such a pancreatic neoplasm occurring in a 57-year-old female who underwent surgical resection. The tumor was histologically as well as immunocytochemically analyzed. The spindle cell pattern, vimentin and actin reactivity confirmed smooth muscle differentiation. On the basis of the degree of cellular atypias and the mitotic counts, the malignant potential of the tumor was assessed. Sharp demarcation of the growth appearing characteristic for this type of pancreatic neoplasia with no invasion into the surrounding organs enabled complete excision in spite of the large dimensions of the tumor.
起源于胰腺的平滑肌肿瘤是一种极其罕见的肿瘤，具有独特的组织病理学特征和渐进性临床病程。我们报告一例发生在一名57岁女性身上的此类胰腺肿瘤病例，该患者接受了手术切除。对肿瘤进行了组织学和免疫细胞化学分析。梭形细胞形态、波形蛋白和肌动蛋白反应证实了平滑肌分化。根据细胞异型性程度和有丝分裂计数评估肿瘤的恶性潜能。尽管肿瘤体积较大，但这种类型的胰腺肿瘤生长界限清晰，无周围器官侵犯，从而得以完整切除。
