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亚细胞组分对腹水细胞核中DNA酶促甲基化的影响。

The influence of subcellular fractions on the enzymic methylation of DNA in ascites cell nuclei.

作者信息

Burdon R H, Douglas J T

出版信息

Nucleic Acids Res. 1974 Jan;1(1):97-103. doi: 10.1093/nar/1.1.97.

DOI:10.1093/nar/1.1.97
PMID:10793663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC343327/
Abstract

Soluble factors appear to be present in both nuclei and cytoplasm of Krebs 2 ascites tumour cells capable of stimulating the enzyme catalysed methylation of DNA in isolated nuclei from these cells.

摘要

可溶性因子似乎存在于克雷布斯2腹水肿瘤细胞的细胞核和细胞质中,这些因子能够刺激从这些细胞分离出的细胞核中由酶催化的DNA甲基化。

相似文献

1
The influence of subcellular fractions on the enzymic methylation of DNA in ascites cell nuclei.亚细胞组分对腹水细胞核中DNA酶促甲基化的影响。
Nucleic Acids Res. 1974 Jan;1(1):97-103. doi: 10.1093/nar/1.1.97.
2
Differences in the content of actin-binding proteins in subcellular fractions prepared from Krebs II ascites cells.
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Prolonged transcription in a cell-free system involving nuclei and cytoplasm.在一个包含细胞核和细胞质的无细胞系统中的长时间转录。
Proc Natl Acad Sci U S A. 1974 May;71(5):1803-7. doi: 10.1073/pnas.71.5.1803.
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Relative susceptibilities of isotopically labelled and unlabelled nuclei to deoxyribonuclease I.
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In vitro HeLa cell DNA synthesis. II. Partial characterization of soluble factors stimulating nuclear dna synthesis.
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引用本文的文献

1
Fifty years of Nucleic Acids Research.《核酸研究》五十年
Nucleic Acids Res. 2024 Jan 11;52(1):1-3. doi: 10.1093/nar/gkad1156.
2
S-adenosylmethionine: DNA-cytosine 5-methyltransferase from a Novikoff rat hepatoma cell line.S-腺苷甲硫氨酸:来自诺维科夫大鼠肝癌细胞系的DNA胞嘧啶5-甲基转移酶
Nucleic Acids Res. 1975 Oct;2(10):1685-700. doi: 10.1093/nar/2.10.1685.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Studies on the biosynthesis of ribonucleic acid in extracts of mammalian cells.
Biochim Biophys Acta. 1961 Feb 12;47:93-106. doi: 10.1016/0006-3002(61)90833-2.
3
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.用于比色法测定脱氧核糖核酸的二苯胺反应的条件及机制研究。
Biochem J. 1956 Feb;62(2):315-23. doi: 10.1042/bj0620315.
4
The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. X. Bacteriophage T3-induced S-adenosylmethionine cleavage.核糖核酸和脱氧核糖核酸的酶促甲基化作用。X. 噬菌体T3诱导的S-腺苷甲硫氨酸裂解
J Biol Chem. 1966 May 10;241(9):1995-2006.
5
Deoxyribonucleic acid methylase activity in rat spleen.
J Biol Chem. 1968 May 10;243(9):2440-2.
6
Enzymic modification of chromosomal macromolecules. I. DNA and protein methylation in mouse tumour cell chromatin.
Biochim Biophys Acta. 1971 Mar 11;232(2):359-70.
7
The heterogeneity of thymine methyl group origin in DNA pyrimidine isostichs of developing sea urchin embryos.发育中的海胆胚胎DNA嘧啶同列线中胸腺嘧啶甲基基团来源的异质性。
Proc Natl Acad Sci U S A. 1967 May;57(5):1394-400. doi: 10.1073/pnas.57.5.1394.
8
Mechanism of action of rat liver DNA methylase. II. Interaction with single-stranded methyl-acceptor DNA.大鼠肝脏DNA甲基化酶的作用机制。II. 与单链甲基受体DNA的相互作用。
J Mol Biol. 1971 Oct 28;61(2):343-56. doi: 10.1016/0022-2836(71)90384-6.
9
The 5-methylcytosine content of DNA: tissue specificity.DNA的5-甲基胞嘧啶含量:组织特异性
J Cell Physiol. 1971 Aug;78(1):33-6. doi: 10.1002/jcp.1040780106.
10
Deoxyribonucleic acid methylase of mammalian tissues.哺乳动物组织的脱氧核糖核酸甲基化酶。
Biochemistry. 1968 Jan;7(1):280-5. doi: 10.1021/bi00841a034.