Barmada B, Diethrich E B
Heart Lung. 1975 May-Jun;4(3):397-401.
Carbon dioxide gas endarterectomy was first applied in cases of total occlusion of the right coronary artery. The early technique involved removal of the disease core along the entire length of the vessel. At follow-up, progressive changes were observed to cause segmental stenosis within the proximal and middle portions of the vessel which led to complete reocclusion of the artery at 36 months. In every case, however, the distal branches of the endarterectomized arteries appeared unaffected. On the basis of these results, we have modified our technique. The present treatment involves distal endarterectomy with aortocoronary bypass to the endarterectomized segment. This surgical approach is appropriated only in cases of diffuse atherosclerotic involvement of the distal arterial branches. It can be applied to any one of the three main coronary artery branches and has therefore broadened the range of patient selection for direct myocardial revascularization. The operative mortality in our series of 58 patients was 6.9 per cent (4 patients), but all deaths were associated with such aggravating factors as anerurysm formation, valve disease, and the preoperative evolution of myocardial infarction. The associated morbidity rate was 6.8 per cent; two patients had disruption of the sternal wound, and one suffered uncomplicated myocardial infarction. The fourth patient had a myocardial infarction followed by development of conduction defect and required operation for the insertion of a permanent transvenous pacemaker. To date, follow-up indicates a high patency rate among the surviving 54 patients.
二氧化碳气体动脉内膜切除术最初应用于右冠状动脉完全闭塞的病例。早期技术是沿着血管全长切除病变核心。随访时,观察到渐进性变化导致血管近端和中部出现节段性狭窄,最终在36个月时动脉完全再次闭塞。然而,在每种情况下,接受内膜切除术的动脉远端分支似乎未受影响。基于这些结果,我们改进了技术。目前的治疗方法是进行远端动脉内膜切除术,并将主动脉冠状动脉旁路移植到接受内膜切除术的节段。这种手术方法仅适用于远端动脉分支弥漫性动脉粥样硬化累及的病例。它可应用于三支主要冠状动脉分支中的任何一支,因此扩大了直接心肌血运重建的患者选择范围。在我们的58例患者系列中,手术死亡率为6.9%(4例患者),但所有死亡均与诸如动脉瘤形成、瓣膜疾病和术前心肌梗死进展等加重因素相关。相关发病率为6.8%;2例患者胸骨伤口裂开,1例发生无并发症的心肌梗死。第4例患者发生心肌梗死,随后出现传导缺陷,需要手术植入永久性经静脉起搏器。迄今为止,随访显示54例存活患者的通畅率很高。