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非体外循环冠状动脉旁路移植术联合冠状动脉内膜切除术的早期和晚期结果:单中心10年经验

Early and late outcome after off-pump coronary artery bypass graft surgery with coronary endarterectomy: a single-center 10-year experience.

作者信息

Vohra Hunaid A, Kanwar Raj, Khan Tanveer, Dimitri Wade R

机构信息

Department of Cardiothoracic Surgery, Coventry and Warwickshire NHS Trust, Walsgrave Hospital, Coventry, United Kingdom.

出版信息

Ann Thorac Surg. 2006 May;81(5):1691-6. doi: 10.1016/j.athoracsur.2005.12.028.

Abstract

BACKGROUND

We aimed to review the early and late results of off-pump coronary artery bypass graft surgery (OPCABG) with coronary endarterectomy in patients undergoing surgical revascularization at our institution.

METHODS

Between 1995 and 2004, of 680 OPCABG patients in a single surgeon's practice (W.R.D.), 70 patients (10.29%) who underwent concomitant coronary endarterectomy were studied. The mean age was 63.6 +/- 9.29 years. Thirty-three patients (55%) were Canadian Cardiovascular Society class III or IV, and 24 patients (40%) were New York Heart Association class III or IV. Eighteen patients (35%) had impaired left ventricular function. The mean EuroSCORE of these patients was 5.9 +/- 1.8.

RESULTS

Fifty-seven patients (81%) underwent right coronary artery endarterectomy, and 12 patients (17%) underwent left anterior descending artery endarterectomy (8 left interior mammary arteries used as conduits). Four patients (5.7%) had two vessels endarterectomized. The mean number of grafts were 2.0 +/- 0.4. The 30-day mortality rate was 2.85% (n = 2). Three patients (4.3%) suffered from postoperative myocardial infarction, and 3 patients (4.3%) required postoperative intra-aortic balloon pump counterpulsation. Mean intensive therapy unit stay was 17.6 +/- 8.1 hours. Patients were extubated after a mean of 10.38 +/- 4.9 hours. The mean length of hospital stay was 6.1 +/- 2.0 days. Fourteen patients (20%) had postoperative atrial fibrillation, and only 1 patient (1.42%) had a transient stroke with complete recovery. There were no conversions to cardiopulmonary bypass. A mean of 0.86 +/- 0.17 units of blood were transfused postoperatively. There was one reopening for bleeding, and 1 patient had renal failure requiring hemofiltration. The median follow-up was 4.91 years, 90% of patients were angina free, and the actuarial survival at 10 years was 78.04% +/- 7.6%.

CONCLUSIONS

Off-pump coronary artery bypass graft survery with coronary endarterectomy is feasible and achieves surgical revascularization in patients with diffuse coronary artery disease.

摘要

背景

我们旨在回顾我院接受外科血运重建术的患者,在非体外循环冠状动脉旁路移植术(OPCABG)联合冠状动脉内膜切除术治疗后的早期和晚期结果。

方法

1995年至2004年间,在一位外科医生(W.R.D.)实施的680例OPCABG患者中,对70例(10.29%)同期接受冠状动脉内膜切除术的患者进行了研究。平均年龄为63.6±9.29岁。33例(55%)患者为加拿大心血管学会III或IV级,24例(40%)患者为纽约心脏协会III或IV级。18例(35%)患者左心室功能受损。这些患者的平均欧洲心脏手术风险评估系统(EuroSCORE)评分为5.9±1.8。

结果

57例(81%)患者接受了右冠状动脉内膜切除术,12例(17%)患者接受了左前降支动脉内膜切除术(8例使用左内乳动脉作为移植血管)。4例(5.7%)患者有两支血管接受了内膜切除术。平均移植血管数量为2.0±0.4。30天死亡率为2.85%(n = 2)。3例(4.3%)患者发生术后心肌梗死,3例(4.3%)患者术后需要主动脉内球囊反搏。平均重症监护病房停留时间为17.6±8.1小时。患者平均在10.38±4.9小时后拔除气管插管。平均住院时间为6.1±2.0天。14例(20%)患者发生术后房颤,只有1例(1.42%)患者发生短暂性卒中且完全恢复。无一例转为体外循环。术后平均输血0.86±0.17单位。有1例因出血再次手术,1例患者发生肾衰竭需要血液滤过。中位随访时间为4.91年,90%的患者无心绞痛,10年实际生存率为78.04%±7.6%。

结论

非体外循环冠状动脉旁路移植术联合冠状动脉内膜切除术是可行的,能够实现弥漫性冠状动脉疾病患者的外科血运重建。

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