Risser D, Uhl A, Stichenwirth M, Hönigschnabl S, Hirz W, Schneider B, Stellwag-Carion C, Klupp N, Vycudilik W, Bauer G
Institute of Forensic Medicine, University of Vienna, Austria.
Addiction. 2000 Mar;95(3):375-82. doi: 10.1046/j.1360-0443.2000.9533758.x.
To investigate the quality of heroin seized in Vienna between 1987 and 1995 and to examine whether there was a relationship between the quality of heroin and the rate of drug-related deaths.
Reports of heroin seizure analysis and post-mortem reports of heroin-related deaths in Vienna from 1987 to 1995 were analysed.
There were 386 seizures of heroin comprising a total weight of 25 640.12 g heroin. All the seizures were in the base form. All seizures also contained a diluent, mainly lactose. Additionally, in 95 seizures caffeine, in four seizures paracetamol and in three seizures metaqualon were detected. Of a total of 764 drug-related deaths 506 cases were classified as heroin-related deaths. In 336 cases other central nervous system-depressant drugs and/or alcohol could be detected in the blood in addition to morphine (polydrug heroin-related deaths). There was evidence of a trend towards greater polydrug involvement during the study period. The age of victims of polydrug heroin-related deaths remained unchanged over time while the age of victims of pure heroin-related deaths decreased significantly. The morphine concentration in the medulla oblongata in heroin-related deaths decreased significantly. Finally, there was no statistically significant relationship between the rate of heroin-related deaths per year and the diacetylmorphine concentration of heroin seizures in that year.
The results did not substantiate the widely held belief that increases in heroin-related deaths could be explained by an increase in the quality of heroin.
调查1987年至1995年间在维也纳查获的海洛因质量,并检验海洛因质量与毒品相关死亡率之间是否存在关联。
分析了1987年至1995年维也纳海洛因查获分析报告及海洛因相关死亡的尸检报告。
共查获386起海洛因,总重25640.12克海洛因。所有查获的海洛因均为基本形式。所有查获的海洛因还含有稀释剂,主要是乳糖。此外,在95起查获中检测到咖啡因,4起查获中检测到对乙酰氨基酚,3起查获中检测到甲喹酮。在总共764例与毒品相关的死亡中,506例被归类为海洛因相关死亡。在336例病例中,除吗啡外,血液中还可检测到其他中枢神经系统抑制药物和/或酒精(多药海洛因相关死亡)。有证据表明,在研究期间多药使用的趋势有所增加。多药海洛因相关死亡受害者的年龄随时间保持不变,而单纯海洛因相关死亡受害者的年龄则显著下降。海洛因相关死亡中延髓的吗啡浓度显著下降。最后,每年海洛因相关死亡率与当年查获海洛因的二乙酰吗啡浓度之间没有统计学上的显著关系。
结果并未证实普遍持有的观点,即海洛因相关死亡人数的增加可归因于海洛因质量的提高。