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街头海洛因纯度与毒品相关紧急情况及/或毒品相关死亡之间存在关联吗?来自奥地利维也纳的一项分析。

Is there a relationship between street heroin purity and drug-related emergencies and/or drug-related deaths? An analysis from Vienna, Austria.

作者信息

Risser Daniele, Uhl Alfred, Oberndorfer Felicitas, Hönigschnabl Selma, Stichenwirth Martin, Hirz Robert, Sebald Dieter

机构信息

Department of Forensic Medicine, Medical University of Vienna, Sensengasse 2, 1090 Vienna, Austria.

出版信息

J Forensic Sci. 2007 Sep;52(5):1171-6. doi: 10.1111/j.1556-4029.2007.00507.x. Epub 2007 Jul 21.

Abstract

This study examines the quality of street heroin seized in Vienna in 1999 and whether there was a relationship between the purity of street heroin and the number of heroin-related emergencies as well as the number of heroin-related deaths. Street heroin confiscated by the Viennese police, run-sheets of drug-related emergencies, and postmortem reports of drug-related deaths in Vienna in 1999 were analyzed. A total of 415 retail samples with a total weight of 128.02 g contained a median percentage of 6.5% diacetylmorphine (range: 0.0-47.0%). All the samples contained a diluent, mainly lactose, as well as adulterants, such as caffeine and/or paracetamol. During the study period, 75 heroin-related deaths and 387 heroin-related emergencies were registered in Vienna. Time-series analysis revealed no statistically significant relationship between the rate of heroin-related incidents and the diacetylmorphine concentration of street heroin samples confiscated in Vienna in 1999. The widely held belief that the number of heroin-related deaths could be explained simply through fluctuations in the purity of street heroin could not be substantiated, even though the results of this study do not rule out an association between the purity of heroin and heroin-related deaths/emergencies.

摘要

本研究调查了1999年在维也纳查获的街头海洛因的质量,以及街头海洛因的纯度与海洛因相关紧急情况的数量和海洛因相关死亡人数之间是否存在关联。对维也纳警方没收的街头海洛因、1999年维也纳与毒品相关紧急情况的记录表以及与毒品相关死亡的尸检报告进行了分析。总共415个零售样本,总重128.02克,二乙酰吗啡的中位数百分比为6.5%(范围:0.0 - 47.0%)。所有样本都含有稀释剂,主要是乳糖,以及掺杂物,如咖啡因和/或对乙酰氨基酚。在研究期间,维也纳记录了75起与海洛因相关的死亡和387起与海洛因相关的紧急情况。时间序列分析显示,1999年在维也纳没收的街头海洛因样本中,海洛因相关事件的发生率与二乙酰吗啡浓度之间没有统计学上的显著关联。尽管本研究的结果不排除海洛因纯度与海洛因相关死亡/紧急情况之间存在关联,但普遍认为海洛因相关死亡人数可以简单地通过街头海洛因纯度的波动来解释这一观点无法得到证实。

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