Segade Buceta X M
Xerencia de Atención Primaria de Santiago, A Coruña.
Aten Primaria. 2000 Mar 15;25(4):236-41. doi: 10.1016/s0212-6567(00)78493-9.
To evaluate the impact of the application of objectives relating to the rational use of medication and to assess the possible effect of these objectives on pharmaceutical expenditure.
A non-randomised intervention study with control.
Santiago de Compostela Primary Care (PC) Area.
After the inclusion and exclusion criteria were applied, both the intervention group (IG) and the control group (CG) consisted of 31 doctors. Those in the IG belonged to the reformed PC model, whereas those in the CG did not.
Four blocks of objectives on the rational use of medication were included in the Pact signed by reformed-model doctors and the management. The study lasted three years (1996-1998) for the objective of lowering the prescription of low-therapeutic-utility (LTU) drugs, and two years (1997-1998) for lowering the prescription of antihypertensives, Triflusal and quinolones.
The difference between both groups was 1.7 fewer packs of LTU drugs per 1000 users and per day in the IG (95% CI, 0.9-2.6) and 1768 pesetas less (95% CI, 801-2733). These differences were still greater among pensioners. The difference between the two groups in terms of total pharmaceutical cost was 7379 pesetas less in the IG (95% CI, 708-14,049) than in the CG. The differences between the groups for the remaining objectives (antihypertensives, Triflusal and quinolones) in no case reached statistical significance.
The pharmaceutical objectives of the pact were partly achieved: a drop in LTU drug prescription was seen, with an indirect reduction in overall expenditure, but no differences were found in the prescription of antihypertensives, triflusal or quinolones.
评估与合理用药相关目标的应用影响,并评估这些目标对药品支出的可能影响。
一项有对照的非随机干预研究。
圣地亚哥德孔波斯特拉初级保健(PC)区。
在应用纳入和排除标准后,干预组(IG)和对照组(CG)均由31名医生组成。干预组医生属于改革后的初级保健模式,而对照组医生不属于该模式。
改革后模式的医生与管理层签署的协议中纳入了四个合理用药目标板块。为降低低治疗效用(LTU)药物的处方量,该研究持续了三年(1996 - 1998年);为降低抗高血压药物、曲氟尿苷和喹诺酮类药物的处方量,研究持续了两年(1997 - 1998年)。
干预组每1000名使用者每天的LTU药物处方量比对照组少1.7包(95%置信区间,0.9 - 2.6),费用少1768比塞塔(95%置信区间,801 - 2733)。这些差异在退休人员中更大。干预组的药品总费用比对照组少7379比塞塔(95%置信区间,708 - 14,049)。两组在其他目标(抗高血压药物、曲氟尿苷和喹诺酮类药物)方面的差异均未达到统计学意义。
该协议中的药品目标部分实现:LTU药物处方量有所下降,总体支出间接减少,但在抗高血压药物、曲氟尿苷或喹诺酮类药物的处方量上未发现差异。