Regeneration of lymphatic vessels and lipometabolism in an experimental rat model of extensive dissection of the abdominal periaortic lymphatic vessels and lymph nodes.

The present study was conducted to analyze the regeneration of lymphatic vessels and lipometabolism in an experimental rat model of extensive dissection of the abdominal periaortic lymphatic vessels and lymph nodes from the renal artery to the mesenteric and celiac artery. Findings showing the regeneration of mesenteric lymphatic vessels were classified as complete, incomplete, or no regeneration. The incomplete regeneration of fine irregular lymphatic vessels was observed in all rats, 2 and 3 weeks postoperatively. At the same time, triglyceride (TG) was found to be significantly lower (P < 0.05) in the rats that were given extensive dissection than in the control group, due to chylomicron blockade after lymphatic dissection. The TG recovered to within the normal range around 4 weeks postoperatively following the growth of fine regenerated lymphatic vessels or collateral route formation.