Neilson J P, Alfirevic Z
Department of Obstetrics and Gynaecology, University of Liverpool, Liverpool, UK, L69 3BX.
Cochrane Database Syst Rev. 2000(2):CD000073. doi: 10.1002/14651858.CD000073.
Abnormal waveforms from Doppler ultrasound may indicate poor fetal prognosis. It is also possible that Doppler ultrasound could encourage inappropriate early delivery.
The objective of this review was to assess the effects of Doppler ultrasound in high risk pregnancies on obstetric care and fetal outcomes.
We searched the Cochrane Pregnancy and Childbirth Group trials register.
Randomised trials of Doppler ultrasound for the investigation of umbilical artery waveforms in high risk pregnancies compared to no Doppler ultrasound.
Trial quality was assessed and data were extracted by both reviewers. Study authors were contacted for additional information.
Eleven studies involving nearly 7000 women were included. The trials were generally of good quality. Compared to no Doppler ultrasound, Doppler ultrasound in high risk pregnancy (especially those complicated by hypertension or presumed impaired fetal growth) was associated with a trend to a reduction in perinatal deaths (odds ratio 0.71, 95% confidence interval 0.50 to 1.01). The use of Doppler ultrasound was also associated with fewer inductions of labour (odds ratio 0.83, 95% confidence interval 0.74 to 0.93) and fewer admissions to hospital (odds ratio 0.56, 95% 0.43 to 0.72), without reports of adverse effects. No difference was found for fetal distress in labour (odds ratio 0.81, 95% confidence interval 0.59 to 1.13) or caesarean delivery (odds ratio 0.94, 95% 0.82 to 1.06).
REVIEWER'S CONCLUSIONS: The use of Doppler ultrasound in high risk pregnancies appears to improve a number of obstetric care outcomes and appears promising in helping to reducing perinatal deaths.
多普勒超声的异常波形可能表明胎儿预后不良。多普勒超声也有可能促使不适当的早产。
本综述的目的是评估高危妊娠中多普勒超声对产科护理和胎儿结局的影响。
我们检索了Cochrane妊娠与分娩组试验注册库。
与未使用多普勒超声相比,对高危妊娠中脐动脉波形进行研究的多普勒超声随机试验。
两位综述作者评估试验质量并提取数据。联系研究作者获取更多信息。
纳入了11项涉及近7000名女性的研究。这些试验质量总体良好。与未使用多普勒超声相比,高危妊娠(尤其是合并高血压或推测胎儿生长受限的妊娠)中使用多普勒超声有降低围产期死亡的趋势(比值比0.71,95%置信区间0.50至1.01)。使用多普勒超声还与较少的引产(比值比0.83,95%置信区间0.74至0.93)和较少的住院(比值比0.56,95%置信区间0.43至0.72)相关,且无不良反应报告。在产时胎儿窘迫(比值比0.81,95%置信区间0.59至1.13)或剖宫产(比值比0.94,95%置信区间0.82至1.06)方面未发现差异。
高危妊娠中使用多普勒超声似乎能改善一些产科护理结局,在帮助降低围产期死亡方面似乎很有前景。