Hagen K B, Hilde G, Jamtvedt G, Winnem M
Health Services Research Unit, National Institute of Public Health, P.O. Box 4404 Torshov, N-0403 Oslo, Norway.
Cochrane Database Syst Rev. 2000(2):CD001254. doi: 10.1002/14651858.CD001254.
Low back pain is a common reason for consulting a general practitioner, and advice on daily activities constitutes an important part in the primary care management of low back pain.
To assess the effects of bed rest for patients with acute low back pain or sciatica.
We searched the Cochrane Musculoskeletal Group trial register, Cochrane Controlled Trials Register, MEDLINE, Embase, Sport, Scisearch, and reference lists of relevant articles. We also contacted authors of relevant articles. Date of the most recent searches: December 1998.
We included all randomised studies or quasi randomised studies where at least one comparison group of adult patients with acute low back pain with or without radiation of pain below the knee was advised to rest in bed for at least two days and one group was not, or where comparison groups were advised to stay in bed for different lengths of time. The main outcomes of interest were pain, functional status, recovery and return to work.
Two reviewers independently selected trials for inclusion, assessed the validity of included trials and extracted data. Investigators were contacted to obtain missing information.
Nine trials with a total of 1435 patients were included. Five trials met all four validity criteria and were assessed to have low risk of bias, while four trials were assessed to have moderate to high risk of bias. Four trials compared bed rest with advice to stay active, and overall the results were heterogeneous. Overall results from two high quality studies indicate no difference in pain intensity at three weeks follow-up [Standardized Mean Difference 0.0 (95%CI: -0.3, 0.2)], and a small difference in functional status in favour of staying active [Weighted Mean Difference 3.2 (on a 0-100 scale) (95%CI 0.6, 5.8)]. Two high quality trials reported no differences in pain intensity between two to three days of bed rest and seven days of bed rest. Another two high-quality trials found no differences between bed rest and exercises in pain intensity or functional status.
REVIEWER'S CONCLUSIONS: Bed rest compared to acvice to stay active will at best have small effects, and at worst might have small harmful effects on acute LBP. Differences in effects of advice to stay in bed compared with advice to stay active are small for patients with low back pain with or without sciatica. There is not an important difference in the effects of bed rest compared with exercises in the treatment of acute low back pain, or seven days compared with two to three days of bed rest in patients with low back pain of different duration with and without radiating pain.
腰痛是患者咨询全科医生的常见原因,关于日常活动的建议是腰痛初级护理管理的重要组成部分。
评估卧床休息对急性腰痛或坐骨神经痛患者的影响。
我们检索了Cochrane肌肉骨骼组试验注册库、Cochrane对照试验注册库、MEDLINE、Embase、Sport、Scisearch以及相关文章的参考文献列表。我们还联系了相关文章的作者。最近一次检索日期:1998年12月。
我们纳入了所有随机研究或半随机研究,其中至少有一组成年急性腰痛患者(伴或不伴有膝以下疼痛放射)被建议卧床休息至少两天,另一组则未被如此建议,或者不同组被建议卧床休息的时间长度不同。主要关注的结局是疼痛、功能状态、恢复情况和重返工作岗位。
两名综述作者独立选择纳入试验,评估纳入试验的有效性并提取数据。联系研究者以获取缺失信息。
纳入了9项试验,共1435例患者。5项试验符合所有四项有效性标准,评估为偏倚风险低,而4项试验评估为中度至高偏倚风险。4项试验比较了卧床休息与保持活动的建议,总体结果具有异质性。两项高质量研究的总体结果表明,在三周随访时疼痛强度无差异[标准化均数差0.0(95%CI:-0.3,0.2)],且在功能状态方面有小的差异,有利于保持活动[加权均数差3.2(0 - 100量表)(95%CI 0.6,5.8)]。两项高质量试验报告卧床休息两天至三天与七天在疼痛强度上无差异。另外两项高质量试验发现卧床休息与锻炼在疼痛强度或功能状态方面无差异。
与保持活动的建议相比,卧床休息至多有微小效果,最坏的情况可能对急性腰痛有微小有害影响。对于伴有或不伴有坐骨神经痛的腰痛患者,卧床休息建议与保持活动建议的效果差异很小。在急性腰痛治疗中,卧床休息与锻炼的效果没有重要差异,对于不同病程且伴有或不伴有放射痛的腰痛患者,卧床休息七天与两天至三天也没有重要差异。