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医生关于戒烟的建议。

Physician advice for smoking cessation.

作者信息

Silagy C

机构信息

Monash Institute of Public Health and Health Service Research, Monash Medical Centre, Locked Bag 29, Clayton, Victoria, Australia, 3168.

出版信息

Cochrane Database Syst Rev. 2000(2):CD000165. doi: 10.1002/14651858.CD000165.

Abstract

BACKGROUND

Health care professionals frequently advise patients to improve their health by stopping smoking. Such advice may be brief, or part of more intensive interventions.

OBJECTIVES

The aims of this review were to assess the effectiveness of advice from physicians in promoting smoking cessation; to compare minimal interventions by physicians with more intensive interventions; to assess the effectiveness of various aids to advice in promoting smoking cessation and to determine the effect of anti-smoking advice on disease specific and all cause mortality.

SEARCH STRATEGY

We searched the Cochrane Tobacco Addiction Group trials register and the Cochrane Controlled Trials Register. Date of the most recent searches: October 1998.

SELECTION CRITERIA

Randomised trials of smoking cessation advice from a medical practitioner in which abstinence was assessed at least six months after advice was first provided.

DATA COLLECTION AND ANALYSIS

We extracted data in duplicate on the setting in which advice was given, type of advice given (minimal or intensive), and whether aids to advice were used, the outcome measures, method of randomisation and completeness of followup. The main outcome measure was abstinence from smoking after at least six months follow-up. We used the most rigorous definition of abstinence in each trial, and biochemically validated rates where available. Subjects lost to follow-up were counted as smokers. Where possible, meta-analysis was performed using a fixed effects model.

MAIN RESULTS

We identified thirty-one trials, conducted between 1972 and 1997, including over 26,000 smokers. In some trials, subjects were at risk of specified diseases (chest disease, diabetes, ischaemic heart disease), but most were from unselected populations. The most common setting for delivery of advice was primary care. Other settings included hospital wards and outpatient clinics, and industrial clinics. Pooled data from 16 trials of brief advice versus no advice (or usual care) revealed a small but significant increase in the odds of quitting (odds ratio 1.69, 95% confidence interval 1.45 to 1.98). This equates to an absolute difference in the cessation rate of about 2.5%. There was insufficient evidence, from indirect comparisons, to establish a significant difference in the effectiveness of physician advice according to the intensity of the intervention, the amount of follow-up provided, and whether or not various aids were used at the time of the consultation in addition to providing advice. However, direct comparison of intensive versus minimal advice showed a small advantage of intensive advice (odds ratio 1.44, 95% confidence interval 1.23 to 1.68). In one study which determined the effect of smoking advice on mortality at twenty years, there were no statistically significant differences in death rates in the group receiving advice.

REVIEWER'S CONCLUSIONS: Simple advice has a small effect on cessation rates. Additional manoeuvres appear to have only a small effect, though more intensive interventions are marginally more effective than minimal interventions.

摘要

背景

医疗保健专业人员经常建议患者通过戒烟来改善健康状况。此类建议可能较为简短,或是更强化干预措施的一部分。

目的

本综述的目的是评估医生建议在促进戒烟方面的有效性;比较医生的最小干预与更强化干预;评估各种辅助建议手段在促进戒烟方面的有效性,并确定戒烟建议对特定疾病和全因死亡率的影响。

检索策略

我们检索了Cochrane烟草成瘾小组试验注册库和Cochrane对照试验注册库。最近一次检索日期为1998年10月。

入选标准

关于医生戒烟建议的随机试验,其中在首次提供建议后至少六个月评估戒烟情况。

数据收集与分析

我们对提供建议的环境、所提供建议的类型(最小或强化)、是否使用辅助建议手段、结果测量、随机化方法以及随访完整性进行了重复数据提取。主要结果测量指标是至少六个月随访后的戒烟情况。我们在每个试验中使用了最严格的戒烟定义,并在可行的情况下采用生化验证率。失访的受试者被计为吸烟者。在可能的情况下,使用固定效应模型进行荟萃分析。

主要结果

我们确定了1972年至1997年间进行的31项试验,涉及超过26000名吸烟者。在一些试验中,受试者存在特定疾病(胸部疾病、糖尿病、缺血性心脏病)风险,但大多数来自未经过筛选的人群。提供建议最常见的环境是初级保健。其他环境包括医院病房和门诊诊所,以及工业诊所。16项关于简短建议与无建议(或常规护理)对比试验的汇总数据显示,戒烟几率有小幅但显著的增加(优势比1.69,95%置信区间1.45至1.98)。这相当于戒烟率的绝对差异约为2.5%。从间接比较中没有足够证据表明,根据干预强度、提供的随访量以及在咨询时除提供建议外是否使用各种辅助手段,医生建议的有效性存在显著差异。然而,强化建议与最小建议的直接比较显示强化建议有小幅优势(优势比1.44,95%置信区间1.23至1.68)。在一项确定吸烟建议对20年死亡率影响的研究中,接受建议组的死亡率没有统计学上的显著差异。

综述作者结论

简单建议对戒烟率有小的影响。额外的措施似乎只有小的影响,尽管更强化的干预比最小干预略为有效。

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