Lancaster T, Stead L F
ICRF General Practice Research Group, Division of Public Health and Primary Health Care, Institute of Health Sciences, Old Road, Headington, Oxford, UK, OX3 7LF.
Cochrane Database Syst Rev. 2002(3):CD001118. doi: 10.1002/14651858.CD001118.
Many smokers give up smoking on their own, but materials giving advice and information may help them and increase the number who quit successfully.
The aims of this review were to determine the effectiveness of different forms of self-help materials, compared with no treatment and with other minimal contact strategies; the effectiveness of adjuncts to self-help, such as computer generated feedback, telephone hotlines and pharmacotherapy; and the effectiveness of approaches tailored to the individual compared with non-tailored materials.
We searched the Cochrane Tobacco Addiction Group trials register using the terms 'self-help', 'manual*' or 'booklet*'. Date of the most recent search March 2002.
We included randomised trials of smoking cessation with follow-up of at least six months, where at least one arm tested a self-help intervention. We defined self-help as structured programming for smokers trying to quit without intensive contact with a therapist.
We extracted data in duplicate on the type of subjects, the nature of the self-help materials, the amount of face to face contact given to subjects and to controls, outcome measures, method of randomisation, and completeness of follow-up. The main outcome measure was abstinence from smoking after at least six months follow-up in patients smoking at baseline. We used the most rigorous definition of abstinence in each trial, and biochemically validated rates when available. Where appropriate, we performed meta-analysis using a fixed effects model.
We identified fifty-one trials. Thirty two compared self-help materials to no intervention or tested materials used in addition to advice. In eleven trials in which self-help was compared to no intervention there was a pooled effect that just reached statistical significance (odds ratio 1.24, 95% confidence interval 1.07 to 1.45) This analysis excluded one trial with a strongly positive outcome that introduced significant heterogeneity. Four further trials in which the control group received alternative written materials did not show evidence for an effect of the smoking self-help materials. We failed to find evidence of benefit from adding self-help materials to face to face advice, or to nicotine replacement therapy. There was evidence from fourteen trials using materials tailored for the characteristics of individual smokers that such personalised materials were more effective than standard manuals (ten trials, odds ratio 1.36, 95% confidence interval 1.13 to 1.64) or no materials (three trials, odds ratio 1.80, 95% confidence interval 1.46 to 2.23). A small numbers of trials failed to detect benefit from using additional materials or targetted materials.
REVIEWER'S CONCLUSIONS: Standard self-help materials may increase quit rates compared to no intervention, but the effect is likely to be small. We failed to find evidence that they have an additional benefit when used alongside other interventions such as advice from a health care professional, or nicotine replacement therapy. There is evidence that materials that are tailored for individual smokers are more effective.
许多吸烟者会自行戒烟,但提供建议和信息的材料可能会对他们有所帮助,并增加成功戒烟的人数。
本综述的目的是确定不同形式的自助材料与不治疗及其他最低限度接触策略相比的有效性;自助辅助手段(如计算机生成的反馈、电话热线和药物治疗)的有效性;以及针对个体的方法与非定制材料相比的有效性。
我们使用“自助”、“手册*”或“小册子*”等术语检索了Cochrane烟草成瘾组试验注册库。最近一次检索日期为2002年3月。
我们纳入了戒烟的随机试验,随访至少6个月,其中至少有一组测试了自助干预措施。我们将自助定义为为试图戒烟的吸烟者提供的结构化程序,而无需与治疗师进行密集接触。
我们对受试者类型、自助材料的性质、给予受试者和对照组的面对面接触量、结局指标、随机化方法以及随访完整性进行了重复数据提取。主要结局指标是基线时吸烟的患者在至少6个月随访后戒烟情况。我们在每个试验中使用了最严格的戒烟定义,并在可获得时使用生化验证率。在适当情况下,我们使用固定效应模型进行荟萃分析。
我们确定了51项试验。32项试验将自助材料与无干预措施进行了比较,或测试了除建议之外使用的材料。在11项将自助与无干预措施进行比较的试验中,汇总效应刚刚达到统计学显著性(优势比1.24,95%置信区间1.07至1.45)。该分析排除了一项具有强阳性结果且引入显著异质性的试验。另外四项试验中,对照组接受了替代书面材料,未显示吸烟自助材料有效果的证据。我们未能找到证据表明在面对面建议或尼古丁替代疗法中添加自助材料有好处。14项针对个体吸烟者特征使用材料的试验有证据表明,这种个性化材料比标准手册(10项试验,优势比1.36,95%置信区间1.13至1.64)或无材料(3项试验,优势比1.80,95%置信区间1.46至2.23)更有效。少数试验未能检测到使用额外材料或针对性材料的益处。
与无干预措施相比,标准自助材料可能会提高戒烟率,但效果可能很小。我们未能找到证据表明它们与其他干预措施(如医疗保健专业人员的建议或尼古丁替代疗法)一起使用时具有额外益处。有证据表明,为个体吸烟者量身定制的材料更有效。