Bossa R, Botturi M, Dubini F, Galatulas I
Minerva Med. 1975 Jul 4;66(48):2316-7.
Chloroimipramine in vitro on human lymphocytes stimulated by phytohaemoagglutinin at concentrations from 1 to 10 g/ml leads to mitotic block. Treatment of normal or suprarenalectomized rats with high doses of the drug administered orally leads to a reduction in the weight of the thymus. The hypothesis that chloroimipramine possibly plays a part in immunitary processes is put forward.
氯米帕明在体外，于浓度为1至10微克/毫升时对由植物血凝素刺激的人淋巴细胞会导致有丝分裂阻滞。用高剂量该药物口服治疗正常或肾上腺切除的大鼠会导致胸腺重量减轻。提出了氯米帕明可能在免疫过程中起作用的假说。
