Chaudron J M, Lebacq E
Acta Cardiol. 1975;30(2):137-50.
Electrophysiologic properties of various conduction pathways responsible for preexcitation syndrome are illdefined; they explain the incidence of arrhythmias : supraventricular tachycardia, atrial fibrillation and, in much rarer cases, flutter. The site of Verapamil activity is chiefly the atrioventricular junction, while its action on the refractory period of atrio-ventricular bypass is small and unforeseable. In a patient with type B. W.P.W. syndrome, complicated with atrial flutter Verapamil induced a preferential stimulation through the anomalous pathway. Right BBB which was obvious during the attack of atrial flutter, was hidden by the type B W.P.W. syndrome, the right branch being shunted by the anomalous pathway. The infrequency of atrial flutter in type B W.P.W. syndrome is emphasized.
导致预激综合征的各种传导途径的电生理特性尚不明确；它们解释了心律失常的发生率：室上性心动过速、心房颤动，以及更罕见的心房扑动。维拉帕米的作用部位主要是房室交界区，而其对房室旁路不应期的作用较小且不可预测。在一名合并心房扑动的B型预激综合征患者中，维拉帕米通过异常途径引起优先刺激。心房扑动发作时明显的右束支传导阻滞被B型预激综合征掩盖，右束支被异常途径分流。强调了B型预激综合征中心房扑动的罕见性。
