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酒精在青少年复发及预后中的作用。

The role of alcohol in adolescent relapse and outcome.

作者信息

Brown S A, Tapert S F, Tate S R, Abrantes A M

机构信息

VA San Diego Healthcare System, Department of Psychiatry, University of California, USA.

出版信息

J Psychoactive Drugs. 2000 Jan-Mar;32(1):107-15. doi: 10.1080/02791072.2000.10400216.

Abstract

Although adolescents entering treatment for substance abuse typically use several substances, alcohol is seldom the drug of choice. Given alcohol's role as a gateway substance in the initiation of substance misuse, the authors hypothesize that alcohol is substantially involved in adolescent relapse following substance abuse treatment. One hundred fifty-seven youths (39.5% female, mean age 15.91 years) were recruited from adolescent inpatient alcohol and drug treatment centers and assessed at six and 12 months after discharge. Of the youths studied, 79% had used one or more substances by 12-month follow-up. Although only 1% reported alcohol as their substance of choice while hospitalized, alcohol was involved in 46% of initial posttreatment use episodes. Almost a quarter (23%) of initial posttreatment substance use events involved multiple substances. Initial posttreatment use episodes involving multiple substances and preferred substances were associated with poorer outcomes during the year following treatment both in terms of rate of return to and severity of substance involvement. Youths who initially used only alcohol were also likely to resume harmful levels of substance involvement by one year after treatment. Results suggest two routes, gateway and preferred substance, for adolescents in the resumption of harmful substance use following treatment. This gateway role merits consideration by adolescent substance abuse treatment providers and families of treated youths.

摘要

虽然进入药物滥用治疗的青少年通常会使用多种药物,但酒精很少是他们的首选药物。鉴于酒精在药物滥用初始阶段作为一种入门物质的作用,作者推测酒精在青少年药物滥用治疗后的复发中起着重要作用。从青少年住院酒精和药物治疗中心招募了157名青少年(女性占39.5%,平均年龄15.91岁),并在出院后6个月和12个月进行评估。在接受研究的青少年中,79%在12个月的随访中使用了一种或多种药物。虽然只有1%的青少年在住院期间将酒精作为他们选择的药物,但酒精参与了46%的初始治疗后用药事件。几乎四分之一(23%)的初始治疗后药物使用事件涉及多种药物。初始治疗后涉及多种药物和首选药物的用药事件,在治疗后的一年里,无论是在复发率还是药物使用的严重程度方面,都与较差的结果相关。最初只使用酒精的青少年在治疗一年后也可能恢复到有害的药物使用水平。结果表明,青少年在治疗后恢复有害药物使用有两条途径,即入门物质途径和首选药物途径。这种入门物质的作用值得青少年药物滥用治疗提供者和接受治疗青少年的家庭考虑。

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