Ooiwa H, Miyazawa T, Yamanishi Y, Hiyama K, Ishioka S, Yamakido M
Department of Pulmonary Medicine, Hiroshima City Hospital.
Intern Med. 2000 Apr;39(4):320-3. doi: 10.2169/internalmedicine.39.320.
Systemic lupus erythematosus (SLE) is sometimes reported to complicate fatal pulmonary hypertension. A 46-year-old woman, with a ten-year history of SLE and pulmonary hypertension, was admitted to our hospital complaining of dyspnea and chest pain. She suffered pulmonary hemorrhage and after steroid pulse therapy, she underwent continuous intravenous infusion of epoprostenol (prostaglandin I2) with corticosteroid for four weeks, which reduced the pulmonary artery pressure and resistance. Following the successful treatment, beraprost sodium, an oral PGI2 analogue, was given and it maintained pulmonary hypertension remittance for four years.
系统性红斑狼疮（SLE）有时据报道会并发致命性肺动脉高压。一名46岁女性，有10年SLE和肺动脉高压病史，因呼吸困难和胸痛入院。她发生了肺出血，在进行类固醇冲击治疗后，她接受了依前列醇（前列腺素I2）与皮质类固醇的持续静脉输注四周，这降低了肺动脉压力和阻力。成功治疗后，给予了口服PGI2类似物贝拉普罗钠，它使肺动脉高压缓解状态维持了四年。
