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[瑞士梅迪-维斯纳病和边界病的血清流行率]

[Seroprevalence of maedi-visna and border disease in Switzerland].

作者信息

Schaller P, Vogt H R, Strasser M, Nettleton P F, Peterhans E, Zanoni R

机构信息

Institut für Veterinär-Virologie, Universität Bern.

出版信息

Schweiz Arch Tierheilkd. 2000 Apr;142(4):145-53.

Abstract

3866 sheep from 226 flocks of breeding associations and 1218 sheep from 15 independent sheep owners were tested for the presence of serum antibodies against Maedi-Visna and Border Disease viruses. The flocks were randomly selected based on the relative proportion and the geographical distribution of the 4 predominant Swiss sheep breeds (Braunköpfiges Fleischschaf, Schwarzbraunes Berg- und Juraschaf, Walliser Schwarznasenschaf, Weisses Alpenschaf). Additionally two smaller breeds were included in the study (Charollais Suisse, Milchschafe). Sera of all sheep older than 1 year were collected together with data characterizing host and management factors. The sera were tested using established ELISAs for detection of antibodies to Maedi-Visna and Bovine Virus Diarrhea/Border Disease viruses. ELISA results of Maedi-Visna serology were confirmed by immunoblotting. 9% of the sheep of breeding associations were antibody-positive for Maedi-Visna virus. The results of the different breeds varied between 0.4% and 36%. A multiple logistic regression procedure identified breed, age, airing in barns, herd size, pasturing on alps and way of keeping the animals during winter as associated factors with individual serostatus. The prevalence of antibodies to Border Disease was 20% in sheep of breeding associations and 65% in those of independent sheep owners.

摘要

对来自226个育种协会羊群的3866只绵羊以及来自15位独立绵羊养殖户的1218只绵羊进行了检测,以确定其血清中是否存在抗梅迪-维斯纳病毒和边界病病毒的抗体。这些羊群是根据瑞士4个主要绵羊品种(褐头肉用羊、黑褐山地和汝拉羊、瓦莱州黑鼻羊、白阿尔卑斯羊)的相对比例和地理分布随机挑选的。此外,研究中还纳入了两个较小的品种(瑞士夏洛莱羊、乳用羊)。收集了所有1岁以上绵羊的血清以及表征宿主和管理因素的数据。使用既定的酶联免疫吸附测定法(ELISA)检测血清中抗梅迪-维斯纳病毒和牛病毒性腹泻/边界病病毒的抗体。梅迪-维斯纳血清学的ELISA结果通过免疫印迹法进行了确认。育种协会的绵羊中有9%对梅迪-维斯纳病毒抗体呈阳性。不同品种的结果在0.4%至36%之间。多元逻辑回归程序确定品种、年龄、羊舍通风、畜群规模、在阿尔卑斯山放牧以及冬季饲养方式是与个体血清状态相关的因素。育种协会绵羊中抗边界病抗体的流行率为20%,独立绵羊养殖户的绵羊中为65%。

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