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Brain death and its impact on the donor heart-lessons from animal models.

作者信息

Wilhelm M J, Pratschke J, Laskowski I A, Paz D M, Tilney N L

机构信息

Surgical Research Laboratory, Harvard Medical School, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.

出版信息

J Heart Lung Transplant. 2000 May;19(5):414-8. doi: 10.1016/s1053-2498(00)00073-5.

DOI:10.1016/s1053-2498(00)00073-5
PMID:10808147
Abstract
摘要

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Mitochondrial responses to brain death in solid organ transplant.实体器官移植中脑死亡时的线粒体反应
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Excitation and contraction of cardiac muscle and coronary arteries of brain-dead pigs.脑死亡猪的心肌和冠状动脉的兴奋与收缩
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Intracerebral bleeding in donors is associated with reduced short-term to midterm survival of heart transplant recipients.
供体颅内出血与心脏移植受者短期至中期生存率降低有关。
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Caspase-1 Inhibitor Reduces Pyroptosis Induced by Brain Death in Kidney.半胱天冬酶-1抑制剂可减轻肾脑死亡诱导的细胞焦亡。
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Modulating donor mitochondrial fusion/fission delivers immunoprotective effects in cardiac transplantation.调节供体线粒体融合/分裂可在心脏移植中提供免疫保护作用。
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