Singer M, Busse R, Seib H J, Elster K, Ottenjann R
Dtsch Med Wochenschr. 1975 Nov 7;100(45):2313-6. doi: 10.1055/s-0028-1106540.
247 polyps were removed by electroresection through an endoscope (and 240 recovered) in 160 patients, aged 24-81 years. The histological substrate varied widely. Comparison of histological findings in the biopsy specimen with those of the entire polyp after polypectomy gave differing results in 41 of 87 gastric polyps. Complication rate of endoscopic polypectomy was 1.6%: postoperative bleeding occurred in three, which was treated conservatively, while in one patient ligation of a blood vessel by laparotomy became necessary. There were no perforation or lethal complications. Among three patients with hyperplasiogenic gastric polyps a "borderline lesion" was found in two (early carcinoma type I; adenocarcinoma). In 13 other patients with hyperplasiogenic polyps follow-up examination after one year revealed recurrence in three, absence of polyps in eight. In one patient a small gastric carcinoma (about 1 cm in diameter) was discovered four months later. It is possible that patients with hyperplasiogenic polyps are at a higher risk of cancer. Six-monthly endoscopic observation is, therefore, indicated.
对160例年龄在24至81岁的患者通过内镜下电切除术切除了247枚息肉(240枚完整回收)。组织学类型差异很大。87枚胃息肉中,41枚息肉活检标本的组织学结果与息肉切除术后整个息肉的组织学结果比较存在差异。内镜下息肉切除术的并发症发生率为1.6%:3例发生术后出血,经保守治疗;1例患者需要开腹结扎血管。无穿孔或致命并发症。3例增生性胃息肉患者中,2例发现“交界性病变”(早期I型癌;腺癌)。另外13例增生性息肉患者在1年后的随访检查中,3例复发,8例息肉消失。1例患者在4个月后发现了1例小胃癌(直径约1cm)。增生性息肉患者患癌风险可能更高。因此,建议每6个月进行一次内镜观察。