Lanza F L, Graham D Y, Nelson R S, Godines R, McKechnie J C
Am J Gastroenterol. 1981 May;75(5):345-8.
Seventy-three upper gastrointestinal endoscopic polypectomies were performed in 63 patients over a period of five years. Thiry-eight patients (52%) had adenomatous polyps, two of which contained carcinoma in situ and 26 (36%) were inflammatory in nature. Four lesions were removed from the duodenum. Hemodynamically significant hemorrhage occurred in five cases and persistent symptomatic ulcer in three cases. All complications occurred early in the series and responded to conservative measures. There was no mortality or need for surgical intervention in any case. It was concluded that: 1. upper gastrointestinal tract endoscopic polypectomy is a safe and relatively simple procedure; 2. postprocedural complications can be markedly reduced by prophylactic conservative antiulcer therapy and 3. especially in the area of adenomatous polyps, excision of the entire lesion is superior to biopsy in the detection of early malignancy.
在五年时间里,对63例患者实施了73例上消化道内镜息肉切除术。38例患者(52%)患有腺瘤性息肉,其中2例含有原位癌,26例(36%)本质上为炎性息肉。4个病变来自十二指肠。5例发生了具有血流动力学意义的出血,3例出现了持续性症状性溃疡。所有并发症均在该系列病例的早期出现,并对保守治疗有效。无一例死亡或需要手术干预。得出以下结论:1. 上消化道内镜息肉切除术是一种安全且相对简单的手术;2. 通过预防性保守抗溃疡治疗可显著降低术后并发症;3. 特别是在腺瘤性息肉区域,完整切除病变在早期恶性肿瘤的检测方面优于活检。