Lau H S, Riezebos J, Abas V, Porsius A J, De Boer A
Department of Pharmacoepidemiology & Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences, The Netherlands.
Pharm World Sci. 2000 Feb;22(1):3-9. doi: 10.1023/a:1008705223595.
In recent years the attitudes and practices of euthanasia (E) and physician-assisted suicide (PAS) among health care workers have been evaluated in different countries. There is, however, still an information gap on the role of pharmacists in these matters. The aim of our study was to study the attitudes and practices of E and PAS among pharmacists.
We conducted a nation-wide survey into the practice, including adherence to guidelines, of E and PAS in community and hospital pharmacies (CP and HP) in the Netherlands. Furthermore, the attitude of community pharmacists concerning this subject was evaluated. Anonymous questionnaires were sent to a random sample of 50% (n = 755) of all CP and to all (n = 101) HP.
The response rates were 52% and 51% for CP and HP, respectively. Most of the CP-respondents (95%) agreed with the concept of E and PAS and would dispense drugs for these purposes. When the data were extrapolated to all pharmacies, there were 1351 and 340 dispensing of drugs for E and PAS per year in CP and HP (94% of all requests), respectively. In most cases the pharmacist had been notified of the condition of the patient (CP: 93%, HP 87%) and a written request was obtained (CP: 74%, HP: 79%). The drugs were often handed personally to the physician (CP: 98%, HP: 86%). Involvement of pharmacy technicians was more common in HP than in CP (31% versus 6%). The most frequently dispensed drugs were muscle relaxants with barbiturates (CP: 47%, HP 71%), barbiturates only (CP: 19%, HP: 6.1%), and muscle relaxants with benzodiazepines (CP: 14%, HP: 7.6%).
Most pharmacists are supportive of E and PAS and are prepared to fill prescriptions written for these purposes.
近年来，不同国家对医护人员关于安乐死（E）和医生协助自杀（PAS）的态度及行为进行了评估。然而，关于药剂师在这些问题上所起作用的信息仍存在空白。我们研究的目的是调查药剂师对安乐死和医生协助自杀的态度及行为。
我们在荷兰开展了一项全国性调查，涉及社区药房和医院药房（CP和HP）中安乐死和医生协助自杀的实施情况，包括对指南的遵循情况。此外，还评估了社区药剂师对该主题的态度。向所有社区药房的50%（n = 755）随机样本以及所有医院药房（n = 101）发送了匿名问卷。
社区药房和医院药房的回复率分别为52%和51%。大多数社区药房的受访者（95%）赞同安乐死和医生协助自杀的概念，并愿意为此配药。将数据外推至所有药房后，社区药房和医院药房每年分别有1351次和340次为安乐死和医生协助自杀配药（占所有请求的94%）。在大多数情况下，药剂师已被告知患者的病情（社区药房：93%，医院药房：87%），并获得了书面请求（社区药房：74%，医院药房：79%）。药品通常由药剂师亲自交给医生（社区药房：98%，医院药房：86%）。医院药房中药剂师助手的参与比社区药房更常见（31%对6%）。最常配发的药物是含巴比妥类的肌肉松弛剂（社区药房：47%，医院药房：71%）、仅巴比妥类药物（社区药房：19%，医院药房：6.1%）以及含苯二氮䓬类的肌肉松弛剂（社区药房：14%，医院药房：7.6%）。
大多数药剂师支持安乐死和医生协助自杀，并准备好为这些目的开具的处方配药。
