Herlitz J, Brandrup-Wognsen G, Karlson B W, Sjöland H, Karlsson T, Hartford M, Caidahl K
Division of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Scand Cardiovasc J. 2000;34(1):65-72. doi: 10.1080/14017430050142422.
To investigate the relationships between limitation of physical activity and dyspnoea and chest pain before and 2 years after coronary artery bypass grafting (CABG) and preoperative left ventricular ejection fraction (LVEF), questionnaires were issued to all patients from Western Sweden who underwent CABG during 1988-1991. The analysis comprised 985 patients. Physical activity improved significantly after CABG regardless of the preoperative LVEF. No significant association was found between LVEF and degree of limitation of physical activity before or after surgery. Dyspnoea and chest pain improved markedly, irrespective of LVEF. There was significant association between freedom from dyspnoea and LVEF preoperatively (less dyspnoea with higher LVEF), but not after CABG. The frequency of chest-pain attacks was not related to LVEF, before or after the operation. Thus physical activity, dyspnoea and chest pain improved in the 2 years after CABG irrespective of preoperative LVEF. Absence of dyspnoea was related to LVEF before, but not after surgery, and there was no association between preoperative LVEF and frequency of anginal attacks before or after CABG.
为了研究冠状动脉旁路移植术（CABG）前后及术前左心室射血分数（LVEF）与体力活动受限、呼吸困难和胸痛之间的关系，我们向1988年至1991年间在瑞典西部接受CABG的所有患者发放了问卷。分析纳入了985例患者。无论术前LVEF如何，CABG后体力活动均有显著改善。手术前后，LVEF与体力活动受限程度之间均未发现显著关联。无论LVEF如何，呼吸困难和胸痛均有明显改善。术前呼吸困难的缓解与LVEF显著相关（LVEF越高，呼吸困难越少），但CABG后则不然。手术前后，胸痛发作频率均与LVEF无关。因此，无论术前LVEF如何，CABG后2年内体力活动、呼吸困难和胸痛均有所改善。术前无呼吸困难与LVEF有关，但术后则无关，术前LVEF与CABG前后心绞痛发作频率均无关联。
