难治性重度抑郁症中的白细胞亚群
Leukocyte subsets in treatment-resistant major depression.
作者信息
Kubera M, Van Bockstaele D, Maes M
机构信息
Department of Endocrinology, Institute of Pharmacology, Polish Academy of Sciences, Kraków.
出版信息
Pol J Pharmacol. 1999 Nov-Dec;51(6):547-9.
PMID:10817536
Abstract
Patients with treatment-resistant major depression had a significantly higher percentage of helper CD4+ T cells and immature double positive CD4+CD8+ T cells in their blood, and higher CD4+/CD8+ ratio than healthy controls. These results suggest activation of T helper immuno-response and disturbance in thymus function in these patients.
摘要
难治性重度抑郁症患者血液中辅助性CD4+ T细胞和未成熟双阳性CD4+CD8+ T细胞的百分比显著高于健康对照组，且CD4+/CD8+比值也更高。这些结果表明这些患者存在辅助性T细胞免疫反应激活和胸腺功能紊乱。
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