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难治性重度抑郁症中的白细胞亚群

Leukocyte subsets in treatment-resistant major depression.

作者信息

Kubera M, Van Bockstaele D, Maes M

机构信息

Department of Endocrinology, Institute of Pharmacology, Polish Academy of Sciences, Kraków.

出版信息

Pol J Pharmacol. 1999 Nov-Dec;51(6):547-9.

PMID:10817536
Abstract

Patients with treatment-resistant major depression had a significantly higher percentage of helper CD4+ T cells and immature double positive CD4+CD8+ T cells in their blood, and higher CD4+/CD8+ ratio than healthy controls. These results suggest activation of T helper immuno-response and disturbance in thymus function in these patients.

摘要

难治性重度抑郁症患者血液中辅助性CD4+ T细胞和未成熟双阳性CD4+CD8+ T细胞的百分比显著高于健康对照组，且CD4+/CD8+比值也更高。这些结果表明这些患者存在辅助性T细胞免疫反应激活和胸腺功能紊乱。

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The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems.
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