免疫增生性小肠疾病中的人类白细胞抗原A19、B12
HLA AW19, B12 in immunoproliferative small intestinal disease.
作者信息
Nikbin B, Banisadre M, Ala F, Mojtabai A
出版信息
Gut. 1979 Mar;20(3):226-8. doi: 10.1136/gut.20.3.226.
Abstract
A group of 21 patients with immunoproliferative small intestinal disease (IPSID), 10 with alpha heavy chain paraproteinaemia and 11 without it, were HLA typed. The results were compared with 35 disease controls and 120 normal controls. A significant increase of Aw19 and B12 antigens was noted among the patients compared with the control subjects. The high rate of association of both AW19 and B12 antigens in patients as compared with controls suggests a possible haplotype (Aw19, B12) association with IPSID.
摘要
对一组21例免疫增殖性小肠疾病（IPSID）患者进行了HLA分型，其中10例有α重链副蛋白血症，11例没有。将结果与35例疾病对照者和120例正常对照者进行比较。与对照受试者相比，患者中Aw19和B12抗原显著增加。与对照相比，患者中AW19和B12抗原的高关联率表明可能存在与IPSID相关的单倍型（Aw19，B12）。
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