Suppr超能文献

小鼠对不同组织学类型细胞免疫反应的遗传决定因素。

Genetic determination of the immune response in mice to cells of different histological type.

作者信息

Lavrovsky V A, Viksler V K, Yurchenko Y A, Razvorotnev V A

出版信息

Immunology. 1979 Apr;36(4):835-41.

PMID:108209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1457666/
Abstract

The intensity of the cellular immune response to strong transplantation antigens of the H-2 complex is related to the histological type of cells taken for immunization. Splenic cells from C3H mice immunized BALB/c mice better than cells of non-lymphoid origin from the same donor. The reverse was observed when, instead of BALB/c mice, C57B1/6 and A/He were used in immunization experiments. Analysis of the inheritance of this immunization pattern studied in mice of the first generation from various crosses between strains (BALB/c, C57B1/6 and A/He) and in mice from backcrosses has demonstrated that this immunization pattern is not inherited as a simple Mendelian character. Therefore, it could be supposed that efficiency of immunological control of cells having different histological types, may be genetically determined.

摘要

对H-2复合体强移植抗原的细胞免疫反应强度与用于免疫的细胞组织学类型有关。C3H小鼠的脾细胞对BALB/c小鼠的免疫效果优于同一供体的非淋巴细胞来源的细胞。当在免疫实验中使用C57B1/6和A/He代替BALB/c小鼠时，观察到相反的情况。对第一代小鼠（来自品系BALB/c、C57B1/6和A/He之间的各种杂交）和回交小鼠中这种免疫模式的遗传分析表明，这种免疫模式并非作为简单的孟德尔性状遗传。因此，可以推测，对具有不同组织学类型的细胞进行免疫控制的效率可能是由基因决定的。

相似文献

1
Genetic determination of the immune response in mice to cells of different histological type.小鼠对不同组织学类型细胞免疫反应的遗传决定因素。
Immunology. 1979 Apr;36(4):835-41.
2
[Genetic determination of the immune response of mice to cells of various histological types].[小鼠对不同组织学类型细胞免疫反应的遗传决定因素]
Genetika. 1978;14(1):72-80.
3
Modification of the anti-tumour immune response by suppressor gene products of lymphoid cells.淋巴细胞抑制基因产物对抗肿瘤免疫反应的修饰。
Immunology. 1979 Apr;36(4):711-8.
4
Non-H-2-linked genetic regulation of cytotoxic responses to hapten-modified syngeneic cells. I. Non-H-2-linked Ir gene defect expressed on T cells is not predetermined at the stage of bone marrow cells.对半抗原修饰的同基因细胞细胞毒性反应的非H-2连锁遗传调控。I. T细胞上表达的非H-2连锁Ir基因缺陷在骨髓细胞阶段未预先确定。
J Immunol. 1986 Feb 15;136(4):1178-85.
5
Immune status of autochthonous and adoptively protected mice toward spontaneous and chemically induced tumors.本地小鼠和过继性保护小鼠对自发性和化学诱导性肿瘤的免疫状态。
Cancer Res. 1972 Nov;32(11):2545-50.
6
Autoimmune interstitial nephritis induced in inbred mice. Analysis of mouse tubular basement membrane antigen and genetic control of immune response to it.近交系小鼠诱导的自身免疫性间质性肾炎。小鼠肾小管基底膜抗原分析及其免疫反应的遗传控制。
Am J Pathol. 1988 Aug;132(2):304-18.
7
Correlation of in vitro and in vivo studies of antigens relevant to the control of murine breast cancer.与小鼠乳腺癌控制相关抗原的体外和体内研究的相关性
Cancer Res. 1976 Feb;36(2 pt 2):739-47.
8
A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA.一种新型的同种异体反应的基因调控。小鼠4号染色体上的一个新位点Alan2控制对三种不同同种抗原（C57BL/10、BALB/c和CBA）的混合淋巴细胞反应。
Genes Immun. 2000 Dec;1(8):483-7. doi: 10.1038/sj.gene.6363711.
9
Stimulation of mouse lymphocytes by a mitogen derived from Mycoplasma arthritidis. VI. Detection of a non-MHC gene(s) in the E alpha-bearing RIIIS mouse strain that is associated with a specific lack of T cell responses to the M. arthritidis soluble mitogen.关节炎支原体来源的促有丝分裂原对小鼠淋巴细胞的刺激作用。VI. 在携带Eα的RIIIS小鼠品系中检测到一个非主要组织相容性复合体（MHC）基因，该基因与对关节炎支原体可溶性促有丝分裂原的特异性T细胞应答缺失有关。
J Immunol. 1987 Aug 1;139(3):927-35.
10
Modulation of F1 cytotoxic potentials by graft-vs-host reaction. Cooperative non-H-2- and H-2D region-gene control of F1 natural resistance to graft-vs-host reaction-associated immunosuppression.移植物抗宿主反应对F1细胞毒性潜能的调节。F1对移植物抗宿主反应相关免疫抑制的天然抗性的非H-2和H-2D区域基因协同控制。
J Immunol. 1989 Mar 1;142(5):1495-9.

引用本文的文献

1
Enhanced immune reactivity to hepatoma 22a cells in MTV-infected compared with MTV-free C3H mice.与未感染MTV的C3H小鼠相比，感染MTV的小鼠对肝癌22a细胞的免疫反应增强。
Immunology. 1981 Dec;44(4):671-6.

本文引用的文献

1
Quantitative studies of the sensitivity of normal and neoplastic mouse cells to the cytotoxic action of isoantibodies.正常和肿瘤小鼠细胞对同种抗体细胞毒性作用敏感性的定量研究。
J Exp Med. 1962 Mar 1;115(3):527-53. doi: 10.1084/jem.115.3.527.
2
A microassay for cell-mediated immunity.一种细胞介导免疫的微量测定法。
Transplantation. 1970 Mar;9(3):219-27. doi: 10.1097/00007890-197003000-00005.
3
An immunostimulation theory of tumor development.肿瘤发生的免疫刺激理论。
Transplant Rev. 1971;7:26-54. doi: 10.1111/j.1600-065x.1971.tb00462.x.
4
Tumor cytotoxicity in vitro by macrophages from mice infected with mycobacterium bovis strain BCG.牛分枝杆菌卡介苗感染小鼠的巨噬细胞在体外的肿瘤细胞毒性
J Natl Cancer Inst. 1974 Jun;52(6):1887-95. doi: 10.1093/jnci/52.6.1887.
5
Studies on the mechanism of lymphocyte-mediated cytolysis. 3. The role of microfilaments and microtubules.淋巴细胞介导的细胞溶解机制研究。3. 微丝和微管的作用。
J Immunol. 1973 Mar;110(3):771-80.
6
Cytotoxic activity of lymphocytes. 3. Standardization of measurement of cell-mediated lysis.淋巴细胞的细胞毒性活性。3. 细胞介导的细胞溶解测量的标准化。
J Immunol. 1974 Jul;113(1):209-24.
7
Discrimination between neoplastic and non-neoplastic cells in vitro by activated macrophages.活化巨噬细胞在体外对肿瘤细胞和非肿瘤细胞的鉴别
J Natl Cancer Inst. 1974 Nov;53(5):1487-92. doi: 10.1093/jnci/53.5.1487.
8
Lysis of tumor cells by antibody and complement. 1. Lack of correlation between antigen content and lytic susceptibility.抗体和补体对肿瘤细胞的溶解作用。1. 抗原含量与溶解敏感性之间缺乏相关性。
J Natl Cancer Inst. 1973 May;50(5):1313-20. doi: 10.1093/jnci/50.5.1313.
9
Expression of various tumor-specific antigens in polyoma virus-induced tumors.
Cancer Res. 1972 Jan;32(1):1-6.
10
Variation in immunosensitivity of SV40-transformed hamster cells.猿猴病毒40（SV40）转化的仓鼠细胞免疫敏感性的变异
J Immunol. 1971 May;106(5):1295-300.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验