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HIV感染女性阴道毛滴虫再感染的发生率及预测因素

Incidence and predictors of reinfection with Trichomonas vaginalis in HIV-infected women.

作者信息

Niccolai L M, Kopicko J J, Kassie A, Petros H, Clark R A, Kissinger P

机构信息

Louisiana State University Health Sciences Center HIV Outpatient Program, New Orleans, USA.

出版信息

Sex Transm Dis. 2000 May;27(5):284-8. doi: 10.1097/00007435-200005000-00009.

DOI:10.1097/00007435-200005000-00009
PMID:10821602
Abstract

BACKGROUND AND OBJECTIVES

The presence of sexually transmitted infections (STIs) may facilitate transmission of HIV to uninfected partners.

GOAL

To describe the incidence of reinfection with Trichomonas vaginalis in HIV-infected women and to assess predictors of reinfection.

STUDY DESIGN

A retrospective cohort study using data abstracted from medical records of HIV-infected women with at least one diagnosis of trichomoniasis.

RESULTS

Approximately one third (36%) of the study population was reinfected with T vaginalis during the follow-up period, with an incidence of 16.4 reinfections per 100 person years. Significant predictors of reinfection included history of another STI (hazard ratio, 1.52; 95% CI, 1.08-2.14) and becoming pregnant during the follow-up period (hazard ratio, 0.59; 95% CI, 0.39-0.87).

CONCLUSIONS

There is a high rate of reinfection with T vaginalis in HIV-infected women. Further research that includes information on sexual partners should be conducted to better describe the reinfection patterns of trichomoniasis.

摘要

背景与目的

性传播感染(STIs)的存在可能会促使艾滋病毒向未感染的性伴侣传播。

目标

描述艾滋病毒感染女性阴道毛滴虫再感染的发生率,并评估再感染的预测因素。

研究设计

一项回顾性队列研究,使用从至少有一次滴虫病诊断的艾滋病毒感染女性的医疗记录中提取的数据。

结果

在随访期间,约三分之一(36%)的研究人群再次感染阴道毛滴虫,每100人年的再感染发生率为16.4例。再感染的显著预测因素包括有其他性传播感染病史(风险比,1.52;95%置信区间,1.08 - 2.14)以及在随访期间怀孕(风险比,0.59;95%置信区间,0.39 - 0.87)。

结论

艾滋病毒感染女性阴道毛滴虫再感染率很高。应开展进一步研究,纳入性伴侣信息,以更好地描述滴虫病的再感染模式。

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