Alzate L H, Sutachan J J, Hurtado H
Laboratorio de Neurociencias, Instituto Nacional de Salud, Avenida Eldorado, Carrera 50, Zona 6, Santafé de, Bogotá, Colombia.
Neurosci Lett. 2000 May 26;286(1):17-20. doi: 10.1016/s0304-3940(00)01052-1.
Specificity of reinnervation after a peripheral nerve lesion has given rise to considerable controversy. As a contribution to solving this issue we have evaluated the specificity of reinnervation of the peroneal nerve after a complete transection of the sciatic nerve repaired with an 8 mm silicone tube, leaving a 4 mm gap between the nerve stumps. Our findings reveal unspecificity of reinnervation of the distal peroneal branch. This lack of specificity is shown by a random distribution of fibers originating from both proximal branches at the level of the tube and at distal peroneal and tibial branches, argue against specificity of regeneration in this model.
