Krieglstein G K
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Nov 25;197(2):153-8. doi: 10.1007/BF02388781.
Bretylium tosylate was applied topically and intravitreously to rabbit eyes. The topical application of 1, 2, 5 and 10% bretylium tosylate gave a small but significant decrease of the intraocular pressure 6 hrs after treatment. The effects had disappeared, when the eyes were re-examined after 24 hrs. The intravitreous injection of 200 mug of bretylium tosylate caused a more pronounced and prolonged pressure decrease. The results are interpreted in the light of chemical sympathectomy.
将溴苄铵甲苯磺酸盐局部应用于兔眼并玻璃体内注射。分别局部应用1%、2%、5%和10%的溴苄铵甲苯磺酸盐，治疗6小时后眼压有小幅但显著下降。24小时后复查时，这些作用已消失。玻璃体内注射200微克溴苄铵甲苯磺酸盐可引起更明显且持久的眼压下降。根据化学性交感神经切除术对结果进行了解释。
