James P A, al-Shafi K M
Department of Microbiology, Gwent Healthcare NHS Trust, Royal Gwent Hospital, Newport, South Wales, UK.
J Clin Pathol. 2000 Mar;53(3):231-3. doi: 10.1136/jcp.53.3.231.
To investigate the clinical value of anaerobic blood culture.
Blood culture bottles (n = 25,185) submitted for culture over a two year period were reviewed.
The bottles yielded 1992 positive patient episodes, a positive rate of 14.4/1000 hospital admissions. Significantly more isolations were obtained from aerobic than from anaerobic bottles. Twelve of the 38 anaerobic episodes were detected in aerobic bottles. Clinical management was influenced in one of 24 patients whose cultures yielded anaerobes from anaerobic bottles only. For a further six patients it was unlikely that the result had any effect on clinical management.
If aerobic bottles were substituted for the anaerobic bottles, detection of positive patient episodes would increase by at least 6%. A higher yield would be achieved by using two aerobic bottles for routine culture and using anaerobic bottles only for patients where anaerobic culture may influence clinical management.
探讨厌氧血培养的临床价值。
回顾了两年期间提交进行培养的血培养瓶(n = 25,185)。
这些培养瓶检出1992例阳性患者事件,阳性率为每1000例住院患者中有14.4例。需氧培养瓶分离出的菌株明显多于厌氧培养瓶。38例厌氧培养事件中有12例在需氧培养瓶中被检测到。仅在厌氧培养瓶中培养出厌氧菌的24例患者中,有1例的临床管理受到影响。对于另外6例患者,该结果不太可能对临床管理产生任何影响。
如果用需氧培养瓶替代厌氧培养瓶,阳性患者事件的检出率将至少提高6%。通过使用两个需氧培养瓶进行常规培养,仅对厌氧培养可能影响临床管理的患者使用厌氧培养瓶,可获得更高的检出率。