Chan W L, Carolan M G, Fernandes V B, Abbati D P
Department of Nuclear Medicine, Wollongong Hospital, NSW, Australia.
Nucl Med Commun. 2000 Mar;21(3):285-90. doi: 10.1097/00006231-200003000-00013.
The aim of this study was to compare two methods of quantifying 99Tc(m)-methylene diphosphonate uptake in the mandibular condyle. The study groups consisted of 23 patients with mandibular asymmetry and 16 normal volunteers aged 10-30 years. The accuracy and reproducibility of SPET using condyle-to-clivus ratios was compared with planar analysis using condyle-to-L4 (fourth lumbar vertebra) ratios. Quantitative analysis was correlated with semi-quantitative grading by three observers. Normal ranges for condyle-to-L4 and condyle-to-clivus ratios in individuals aged 11 years or over were determined. These ratios are useful in the serial monitoring of patients with condylar hyperplasia to establish when condylar growth has ceased and hence the type of surgery performed. Visual interpretation of condylar activity should use a combination of planar and SPET images and be performed in conjunction with quantitative analysis. Semi-quantitative grading on SPET images detected more subtle differences in condylar activity than planar images (using quantitative analysis as a standard).
本研究的目的是比较两种量化下颌髁突摄取99Tc（m）-亚甲基二膦酸盐的方法。研究组包括23例下颌不对称患者和16名年龄在10至30岁的正常志愿者。将使用髁突与斜坡比值的单光子发射计算机断层显像（SPET）的准确性和可重复性与使用髁突与L4（第四腰椎）比值的平面分析进行比较。定量分析与三位观察者的半定量分级相关。确定了11岁及以上个体髁突与L4及髁突与斜坡比值的正常范围。这些比值在髁突增生患者的系列监测中很有用，可用于确定髁突生长何时停止，从而确定所施行手术的类型。对髁突活性的视觉解读应结合平面图像和SPET图像，并与定量分析一起进行。与平面图像相比（以定量分析为标准），SPET图像上的半定量分级能检测到髁突活性更细微的差异。
