Masel S L, Brennan B A, Turner J H, Cullingford G L, Cullen D J
Department of Gastroenterology, Fremantle Hospital, Western Australia, Australia.
J Gastroenterol Hepatol. 2000 Apr;15(4):457-60. doi: 10.1046/j.1440-1746.2000.02093.x.
A 42-year-old woman presented with a 4-year history of worsening diarrhoea that was watery, profuse and confirmed to be secretory in nature. She had tested positive for phenolphthalein on urinary laxative screening but continued to deny laxative usage. Her vasoactive intestinal polypeptide (VIP) level was subsequently found to be markedly elevated. Despite a normal abdominal ultrasound, a computed tomography scan revealed a 5-cm pancreatic tail mass. Octreotide scanning was used to exclude metastatic disease and she went on to have surgical removal of a localized pancreatic vasoactive intestinal polypeptide-oma which resulted in the complete resolution of her diarrhoea.
一名42岁女性有4年腹泻病史，腹泻症状逐渐加重，呈水样、量大，经证实为分泌性腹泻。她的尿液泻药筛查中酚酞试验呈阳性，但她仍否认使用泻药。随后发现她的血管活性肠肽（VIP）水平显著升高。尽管腹部超声检查正常，但计算机断层扫描显示胰尾有一个5厘米的肿块。使用奥曲肽扫描排除转移性疾病后，她接受了手术切除局部胰腺血管活性肠肽瘤，腹泻症状完全缓解。
