Keller E L
Exp Brain Res. 1976 Mar 15;24(5):459-71. doi: 10.1007/BF00234963.
The behavior of single vestibular nerve fibers from the lateral semicircular canal was recorded during sinusoidal oscillations of the head, during optokinetic stimulation with the head stationary, and during spontaneous oculomotor behavior in the alert monkey. The response of similar fibers to adequate vestibular stimulation was also studied in some of the animals under deeply anesthetized conditions. In the alert animals all units were spontaneously active and their discharge was modulated only by adequate vestibular stimulation. Ipsilateral horizontal rotations of the head were excitatory for all units. No modification of this basic vestibular response by visual stimulation including full-field striped drum rotation was observed. Furthermore no correlation of unit activity with oculomotor function including voluntary saccadic and pursuit eye movements was found in any of the units. The regularity of spontaneous discharge was the most consistent characteristic that differentiated the unit response into types. Most units were very regular in discharge, but a few were very irregular. The averaging of unit discharge over several cycles of oscillatory head rotation showed that the irregular type units were also consistently modulated by adequate vestibular stimulation. Both regular and irregular type units were found in the anesthetized animals. Unimodal distributions of the quantitative values for unit resting discharge rate, sensitivity, and phase relationship were found. The distributions for these three parameters were similar in the units recorded in the anesthetized animals. Thus at least these characteristics of semicircular canal response seem not to be affected by the vestibular efferent system which should be altered or eliminated in the case of the anesthetized animals.
在警觉的猴子头部进行正弦振荡期间、头部静止时进行视动刺激期间以及自发眼动行为期间，记录来自外侧半规管的单个前庭神经纤维的行为。在一些深度麻醉的动物中，也研究了类似纤维对适当前庭刺激的反应。在警觉的动物中，所有单位均自发活动，其放电仅受适当前庭刺激的调节。头部同侧水平旋转对所有单位均具有兴奋性。未观察到包括全视野条纹鼓旋转在内的视觉刺激对这种基本前庭反应的改变。此外，在任何单位中均未发现单位活动与包括自愿性扫视和追踪眼动在内的眼动功能之间的相关性。自发放电的规律性是将单位反应区分为不同类型的最一致特征。大多数单位的放电非常规律，但少数单位非常不规律。在几个振荡头部旋转周期内对单位放电进行平均显示，不规则型单位也受到适当前庭刺激的持续调节。在麻醉动物中发现了规则型和不规则型单位。发现单位静息放电率、敏感性和相位关系的定量值呈单峰分布。在麻醉动物中记录的单位中，这三个参数的分布相似。因此，至少半规管反应的这些特征似乎不受前庭传出系统的影响，而在前庭传出系统中，麻醉动物的前庭传出系统应该已经改变或消除。
