Robichon F, Bouchard P, Démonet J, Habib M
Laboratoire d'Etude de l'Apprentissage et du Développement (CNRS ESA 5022), Université de Bourgogne, Dijon, France.
Eur Neurol. 2000;43(4):233-7. doi: 10.1159/000008182.
Using a new method based upon the measurement of four angles, we analyzed the corpus callosum of 23 adult male dyslexics and 25 age-matched controls on MRI sagittal scans. Two out of the four angles measured showed significant differences between the groups that are consistent with previous findings concerning the size of the corpus callosum in dyslexics. In particular, posterior regions are concerned, displaying a lowered corpus callosum in dyslexics. These findings are discussed in relation to cortical parietal asymmetries and possible hormonal events, referring to the testosterone hypothesis, that could occur in utero or in the perinatal period in the dyslexic population.
我们采用一种基于四个角度测量的新方法，在MRI矢状扫描上分析了23名成年男性诵读困难者和25名年龄匹配的对照者的胼胝体。所测量的四个角度中有两个在两组之间显示出显著差异，这与先前关于诵读困难者胼胝体大小的研究结果一致。特别是涉及到后部区域，诵读困难者的胼胝体较低。这些发现结合皮质顶叶不对称性和可能的激素事件进行了讨论，参考了睾酮假说，该假说认为这些事件可能发生在诵读困难人群的子宫内或围产期。
