Ajisaka N, Hara K, Mikuni K, Hara K, Hashimoto H
Bio Research Corporation of Yokohama, Japan.
Biosci Biotechnol Biochem. 2000 Apr;64(4):731-4. doi: 10.1271/bbb.64.731.
In order to investigate the application potential of branched CDs, the solubilizing ability and the stabilizing ability of G2-betaCD and GUG-betaCD were investigated by using twelve terpenes (d-limonene, myrcene, terpinolene, geraniol, l-menthol, nerol, alpha-terpineol, citral, d-citronellal, l-perillaldehyde, (R)-l-carvone, and menthone) as guest compounds. G2-betaCD and GUG-betaCD showed more solubilizing ability for these twelve terpenes than betaCD, and the ability of GUG-betaCD was almost the same as that of G2-betaCD. The stabilizing ability of terpene-GUG-betaCD complexes was different from that of G2-betaCD. GUG-betaCD was superior to G2-betaCD, especially in the solid state. This result may have been caused by the difference in structure of side chain, namely the hydroxymethyl group in G2-betaCD and the carboxyl group in GUG-betaCD.
为了研究支链环糊精的应用潜力，以十二种萜类化合物（d-柠檬烯、月桂烯、萜品油烯、香叶醇、l-薄荷醇、橙花醇、α-萜品醇、柠檬醛、d-香茅醛、l-紫苏醛、(R)-l-香芹酮和薄荷酮）作为客体化合物，研究了G2-β环糊精和GUG-β环糊精的增溶能力和稳定能力。G2-β环糊精和GUG-β环糊精对这十二种萜类化合物的增溶能力比β环糊精更强，且GUG-β环糊精的能力与G2-β环糊精几乎相同。萜类-GUG-β环糊精复合物的稳定能力与G2-β环糊精不同。GUG-β环糊精优于G2-β环糊精，尤其是在固态时。该结果可能是由侧链结构的差异导致的，即G2-β环糊精中的羟甲基和GUG-β环糊精中的羧基。
