Krayenbühl C U, Krayenbühl H P, Rothlin M
Thoraxchir Vask Chir. 1976 Feb;24(1):46-9. doi: 10.1055/s-0028-1095865.
Between 1961 and 1972, 354 patients with atrial septal defect ware treated surgically. Of these 80 patients were aged over 40 years at the time of operation. The hospital mortality was 5%. 2 of these patients had a increased preoperative pulmonary artery systolic pressure (50-75 mmHg), the other 2 had a mitral or tricuspid incompetence. At late follow-up 82% of patients were symptomfree, 18% had slight clinical signs of breathlesness on exertion. The heart size decreased in 37 of 40 patients, the electrocardiographis signs of right ventricular hypertrophy in 23 patients. There was no influence on preexistant dysrhythmias by the operation. It is concluded that patients with atrial septal defect in this age group benefit from surgical closure of the defect.
1961年至1972年间,354例房间隔缺损患者接受了手术治疗。其中80例患者在手术时年龄超过40岁。医院死亡率为5%。这些患者中有2例术前肺动脉收缩压升高(50 - 75 mmHg),另外2例有二尖瓣或三尖瓣关闭不全。在后期随访中,82%的患者无症状,18%的患者有轻微的劳力性呼吸困难临床体征。40例患者中有37例心脏大小减小,23例患者有右心室肥厚的心电图表现。手术对术前已有的心律失常没有影响。结论是该年龄组的房间隔缺损患者从缺损的手术闭合中获益。