Chiba A
Department of Biology, Nippon Dental University School of Dentistry at Niigata, 951-8580, Niigata, Japan.
Neurosci Lett. 2000 Jun 9;286(3):195-8. doi: 10.1016/s0304-3940(00)01122-8.
Previous studies showed immunoreactivities for neuropeptide Y (NPY), molluscan cardioexcitatory tetrapeptide (FMRFamide), and gonadotropin-releasing hormone (GnRH) in the terminal nerve of elasmobranchs. The present immunohistochemical study demonstrated two types of cells, i.e. GnRH- and NPY/FMRFamide-positive cells, in the terminal nerve ganglion of the elasmobranch Scyliorhinus torazame. The second cell type (non-GnRH element) contained a substance with a common structure or epitope recognized by anti-NPY and anti-FMRFamide antibodies. The NPY/FMRFamide-like immunoreactivity was associated with granules 70-130 nm in diameter, found in the cell bodies, axons, and axon endings.
先前的研究表明，在板鳃亚类动物的终末神经中存在神经肽Y（NPY）、软体动物心脏兴奋四肽（FMRF酰胺）和促性腺激素释放激素（GnRH）的免疫反应性。目前的免疫组织化学研究在板鳃亚类动物豹纹鲨的终末神经节中证实了两种类型的细胞，即GnRH阳性细胞和NPY/FMRF酰胺阳性细胞。第二种细胞类型（非GnRH成分）含有一种具有共同结构或表位的物质，该物质可被抗NPY和抗FMRF酰胺抗体识别。NPY/FMRF酰胺样免疫反应性与直径70-130nm的颗粒有关，这些颗粒存在于细胞体、轴突和轴突终末中。
