Potashov L V, Berlin L B, Klimashevskiĭ V F, Sedov V M
Arkh Anat Gistol Embriol. 1976 Feb;70(2):65-8.
The autoradiographic method was used for a comparative study of regeneration of the gastric mucosa after wounding the rat with a preliminary loss of blood and without it. The H3-thymidin label index was determined in the portions of the mucosa of the wound edge and far from it. A histological analysis of healing the wounds failed to reveal any difference in terms of this process in rats with a loss of blood and without it. A momentary massive loss of blood did not influence the strain and intracellular regeneration processes in the healing wound of the stomach: the amount of cells synthesizing DNA at the edges of the gastrotonic wound proved to be the same in experiments both with a loss of blood and without it. The authors believe that it may serve as an indirect evidence of a somewhat exaggerated danger of surgery at the height of gastroduodenal bleeding.
采用放射自显影法，对大鼠胃黏膜在有失血前期和无失血前期受伤后的再生情况进行了比较研究。测定了伤口边缘及远离伤口的黏膜部分的H3-胸腺嘧啶核苷标记指数。对伤口愈合的组织学分析未能发现有失血和无失血大鼠在这一过程方面的任何差异。瞬间大量失血并未影响胃愈合伤口中的应变和细胞内再生过程：在有失血和无失血的实验中，胃紧张性伤口边缘合成DNA的细胞数量证明是相同的。作者认为，这可能间接证明了在胃十二指肠出血高峰期手术的危险在某种程度上被夸大了。
